University of Cincinnati

12/05/2025 | Press release | Distributed by Public on 12/05/2025 11:07

Student-designed AI platform aims to match patients to specific cancer support groups

Student-designed AI platform aims to match patients to specific cancer support groups

Fourth-year medical sciences major built platform and affiliated nonprofit

7 minute read December 5, 2025 Share on facebook Share on Twitter Share on LinkedIn Share on Reddit Print StoryLike

The National Cancer Institute estimates that approximately 25% of all cancer patients also experience depression. However, only approximately 5% of these patients seek treatment with a mental health professional.

Now, the University of Cincinnati is launching a clinical trial testing a student-designed, machine-learning powered platform to match patients with cancer to support groups specifically tailored to their needs and concerns.

Platform development

Siddhant Nagar, OncoSupport founder. Photo provided.

The trial will utilize a platform called OncoSupport, developed by a nonprofit organization of the same name. The nonprofit and AI platform were created by fourth-year UC medical sciences and honors student Siddhant Nagar.

Nagar, of Mason, Ohio, was drawn from an early age to medicine and plans to go to medical school following his undergraduate studies. While working as a patient care assistant at UC Health and volunteering with Blood Cancer United (formerly the Leukemia and Lymphoma Society), he identified the need to improve mental health care infrastructure for patients with cancer.

In the summer of 2023, Nagar developed the first version of the OncoSupport platform and built the initial machine-learning pipeline.

"I really found my niche in machine learning, so I developed a machine-learning algorithm designed to group patients based on clinical and psychosocial similarity," he explained. "It took a very long time to build it, and additional software engineering support has since been brought on to continue advancing the platform."

Trial details

Patients fill out a secure form with information, including the languages they speak, what type of cancer they have and the specific concerns they have, such as a fear of recurrence, the stress of taking care of children while fighting cancer or the lack of a caregiver to help them through their treatment.

The OncoSupport platform then uses its machine learning algorithm to match patients with a support group that should be the best fit for their needs and have fellow patients in the most similar situations.

The Phase 1 trial will enroll 40 to 60 patients being treated for cancer at the University of Cincinnati Cancer Center. All patients will be assigned to different Zoom support groups run by licensed mental health professionals based on the responses they provide to the OncoSupport algorithm.

"This is a feasibility study, analyzing if this is something that cancer patients benefit from and if this is something that in a vacuum patients can generally look at and want to utilize," Nagar said. "Additionally, is it something that's accepted generally by the physicians and the health care atmosphere at UC Health?"

The team will additionally measure a secondary outcome of participants' changes in psychological distress.

Faculty support

Anjanette Wells, PhD. Photo/University of Cincinnati.

Since Nagar is still an undergraduate student, he partnered with University of Cincinnati Cancer Center researchers Anjanette Wells, PhD, and Georgia Anderson, PhD, as co-principal investigators for the trial. Both researchers have clinical oncology social work experience.

"A clinical trial is the gold standard in research, and Siddhant is just extremely bright," said Wells, an associate professor in UC's College of Medicine. "I like the project because it's very innovative in that it intersects in medicine and technology, which is the wave of the future. I like the customization and the tailoring that has gone into it, and I'm excited to be on the project."

Anderson said she is excited to see how the AI platform works in practice, including whether there is such a thing as patients being "too much alike."

Georgia Anderson, PhD. Photo/University of Cincinnati.

"That's what I love about being a social worker, doing psychosocial clinical care, is every time you think you've got it figured out, you learn something new because all people are different and circumstances are always moving," said Anderson, an assistant professor in UC's College of Medicine.

The project is personal for both researchers. Wells' father is currently being treated for multiple myeloma, and Anderson's father passed away from leukemia in 2020. They said the combination of AI-powered assignments and virtual support groups presents an opportunity to make mental health care more accessible for patients like their family members.

"So hopefully, once we find out more about its use, we can open and expand access for a lot more people," Wells said. "My dad is constantly getting information about different resources and support groups, but I think this offers something that would be tailored to him."

"I think the psychosocial needs of cancer patients have been acknowledged more greatly than they have ever in the past, but there's still a lot of room to add to the toolbox," Anderson added. "I don't know if my dad would have been a support group guy, but I think using that technology to match him with other people might have helped give them that extra safety net."

Future goals

Following the Phase 1 feasibility trial, Nagar said he hopes to conduct Phase 2 randomized control trials comparing OncoSupport to standard support group offerings. Long term, his goal is for OncoSupport to be used at every hospital treating patients with cancer in the country to match patients with support for their unique needs.

"I'm most excited to truly fill a gap that I feel has been left alone for a long time," Nagar said. "I think current social support services work really great for a lot of patients, but for some patients, they may not be the best fit for them."

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For more information on the trial and enrollment, please contact Nagar at [email protected].

Featured photo at top of a man in a virtual support group. Photo/SDI Productions/iStock Photo.

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University of Cincinnati published this content on December 05, 2025, and is solely responsible for the information contained herein. Distributed via Public Technologies (PUBT), unedited and unaltered, on December 05, 2025 at 17:07 UTC. If you believe the information included in the content is inaccurate or outdated and requires editing or removal, please contact us at [email protected]