Free Writing Prospectus (Form FWP)

Issuer:

Morgan Stanley

Principal Amount:

$1,500,000,000

Maturity Date:

January 18, 2041

Trade Date:

January 15, 2026

Original Issue Date

(Settlement):

January 20, 2026 (T+2)

Interest Accrual Date:

January 20, 2026

Issue Price (Price to Public):

100.00%

Agents’ Commission:

0.45%

All-in Price:

99.55%

Net Proceeds to Issuer:

$1,493,250,000

Initial Fixed Rate Period:

From and including the Original Issue Date to but excluding the Interest Reset Date

Interest Reset Date:

January 18, 2036

Subsequent Fixed Rate

Period:

From and including the Interest Reset Date to but excluding the Maturity Date

Interest Rate:

The Interest Rate will reset once during the term of the notes and will be as follows: During the Initial Fixed Rate Period, 5.314% per annum; during the Subsequent Fixed Rate Period, the Base Rate plus 1.170% (to be determined by the Calculation Agent on the Reset Determination Date)

Reset Determination Date:

The second Business Day prior to the Interest Reset Date

Base Rate:

Constant Maturity Treasury Rate, as described in the below-referenced preliminary pricing supplement

Spread (Plus or Minus):

Plus 1.170%

Index Maturity:

Five years

Index Currency:

U.S. Dollars

Interest Payment Periods:

Semiannual

Interest Payment Dates:

Each January 18 and July 18, commencing July 18, 2026 to and including the Maturity Date.

Reporting Service:

Bloomberg (Page H15T5Y )

Day Count Convention:

30/360

Optional Redemption:

Optional Make-Whole Redemption, on or after January 24, 2031 (or, if additional notes are issued after the Original Issue Date, on or after the date that is five years and two business days after the original issue date of such additional notes) and prior to January 18, 2036, in whole at any time or in part from time to time, on at least 3 business days’ but not more than 60 calendar days’ prior notice, as described in the below-referenced Prospectus under the heading “Description of Debt Securities—Redemption and Repurchase of Debt Securities—Optional Make-Whole Redemption of Debt Securities,” provided that (A) the make-whole redemption price shall be equal to the greater of: (i) 100% of the principal amount of such notes to be redeemed and (ii) the sum of (a) the present value of the payment of principal on such notes to be redeemed and (b) the present values of the scheduled payments of interest on such notes to be redeemed that would have been payable from the date of redemption to January 18, 2036 (not including any portion of such payments of interest accrued to the date of redemption), each discounted to the date of redemption on a semiannual basis (assuming a 360-day year consisting