noodls browser compatibility check

The security settings of your browser are blocking the execution of scripts.

To use noodls, javascript support must be enabled. Please change your browser's security settings to enable javascript.

If you have changed your browser's security settings, you can click here.

related announcements

Company News

Amazon.com Inc.

Class 2 Device Recall PERCUTANEOUS SHEATH INTRODUCER
Amazon.com Inc.

Tzumi Electronics Recalls FitRx SmartBell Quick-Select Adjustable[...]
Amazon.com Inc.

Class 2 Device Recall ARROW, ARROWGARD AND ARROWGARD BLUE PLUS PRESSURE[...]

Economy, Business and Finance

American Strategic Investment Co.

04/23/2026 | Press release | Distributed by Public on 04/23/2026 14:39

Proxy Statement (Form DEF 14A)

TABLE OF CONTENTS

UNITED STATES
SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

SCHEDULE 14A

Proxy Statement Pursuant to Section 14(a) of the
Securities Exchange Act of 1934

(Amendment No. )

Filed by the Registrant ☒

Filed by a Party other than the Registrant ☐

Check the appropriate box:

☐

Preliminary Proxy Statement

☐

Confidential, for Use of Commission Only (as permitted by Rule 14a-6(e)(2))

☒

Definitive Proxy Statement

☐

Definitive Additional Materials

☐

Soliciting Material under §240.14a-12

AMERICAN STRATEGIC INVESTMENT CO.

(Name of Registrant as Specified in its Charter)

(Name of Person(s) Filing Proxy Statement, If Other Than the Registrant)

Payment of Filing Fee (Check all boxes that apply):

☒

No fee required.

☐

Fee paid previously with preliminary materials.

☐

Fee computed on table in exhibit required by Item 25(b) per Exchange Act Rules 14a-6(i)(1) and 0-11.

TABLE OF CONTENTS

To the Stockholders of American Strategic Investment Co.:

I am pleased to invite you to the 2026 Annual Meeting of Stockholders (the "Annual Meeting") of American Strategic Investment Co., a Maryland corporation (the "Company"), which will be held virtually on June 2, 2026 commencing at 2:00 p.m. Eastern Time. The items of business are listed in the following Notice of Annual Meeting of Stockholders and are more fully addressed in the proxy statement.

At the Annual Meeting you will be asked to elect the persons named in the accompanying proxy statement as Class III directors and to vote on one other proposal as described in the accompanying Notice of 2026 Annual Meeting of Stockholders and proxy statement.

You will be able to attend the Annual Meeting, vote your shares electronically and submit your questions during the meeting via live audio webcast by visiting meetnow.global/MLJAF4H. To participate in the Annual Meeting, you must have your control number that is shown on your Notice of Internet Availability of Proxy Materials or, if you received a printed copy of the proxy materials, on your proxy card or the instructions that accompanied your proxy materials. Stockholders will not be able to physically attend the Annual Meeting.

Details concerning the matters to come before stockholders at the Annual Meeting are described in the accompanying Notice of 2026 Annual Meeting of Stockholders and proxy statement. We will be using the "Notice and Access" method of providing proxy materials to you via the Internet. We believe that this process will provide a convenient and economic way to access the proxy materials and authorize a proxy to vote your shares.

Your vote is very important. Please respond as soon as possible to help us avoid potential delays and additional expenses to solicit votes.

On behalf of the Board of Directors, we appreciate your support.

	Sincerely,
	/s/ Nicholas S. Schorsch, Jr. Nicholas S. Schorsch, Jr. Chief Executive Officer

TABLE OF CONTENTS

222 Bellevue Ave.
Newport, Rhode Island 02840

NOTICE OF ANNUAL MEETING OF STOCKHOLDERS
TO BE HELD ON JUNE 2, 2026

April 23, 2026

To the Stockholders of American Strategic Investment Co.:

I am pleased to invite you to the 2026 Annual Meeting of Stockholders, including any postponement or adjournment thereof (the "Annual Meeting"), of American Strategic Investment Co., a Maryland corporation (the "Company"), which will be held at 2:00 p.m. Eastern Time on June 2, 2026. The Annual Meeting will be a "virtual meeting" of stockholders which will be conducted exclusively online via live webcast. You will be able to attend the Annual Meeting and vote and submit questions during the Annual Meeting via the live webcast by visiting meetnow.global/MLJAF4H.

If you plan to attend the Annual Meeting online, you will need the control number included on the Notice of Internet Availability of Proxy Materials ("Notice of Availability") or, if you requested paper copies, in the instructions printed on your proxy card. Instructions are also described in the accompanying proxy statement. At the Annual Meeting, you will be asked to consider and vote upon on the following matters, as more fully described in the proxy statement accompanying this Notice of the Annual Meeting: (1) the election of two persons to serve on our board of directors (the "Board of Directors") until the 2029 annual meeting of stockholders (the "2029 Annual Meeting") and until their respective successors are duly elected and qualify, (2) the ratification of the appointment of CBIZ CPAs P.C. as the Company's independent registered public accounting firm for the year ending December 31, 2026, (3) a proposal to adopt a non-binding advisory resolution regarding executive compensation and (4) the transaction of such other matters as may properly come before the Annual Meeting. The Board of Directors has fixed the close of business on April 10, 2026 (the "Record Date") as the record date for the Annual Meeting. Only record holders of shares of the Company's Class A common stock, par value $0.01 per share, at the close of business on the record date are entitled to notice of, and to vote at, the Annual Meeting.

For further information regarding the matters to be acted upon at the Annual Meeting, please read the accompanying proxy statement. We are mailing the Notice of Availability to our stockholders of record as of the Record Date instead of paper copies of our proxy statement and 2025 Annual Report in reliance on rules promulgated by the Securities and Exchange Commission that allow the Company to furnish proxy materials to you via the Internet. The Notice of Availability contains instructions on how to access those documents via the Internet. The Notice of Availability also contains instructions on how stockholders can receive a paper copy of our proxy materials, including the proxy statement, our 2025 Annual Report and proxy card. This Notice of the Annual Meeting, the Notice of Availability, proxy statement and form of proxy are being distributed and made available on the Internet on or about April 23, 2026.

Registered stockholders can access proxy materials at www.envisionreports.com/NYC. Beneficial holders can access proxy materials at www.edocumentview.com/NYC. You also may authorize your proxy via the Internet or by telephone by following the instructions on those websites. You may vote during the Annual Meeting by following the instructions available on the meeting website during the meeting. Your attendance alone, without voting, will not be sufficient to revoke a previously authorized proxy.

TABLE OF CONTENTS

You are cordially invited to attend the Annual Meeting. Regardless of whether you own a few or many shares and whether you plan to attend the Annual Meeting in person via webcast or not, it is important that your shares be voted on matters that come before the Annual Meeting.

	By Order of the Board of Directors,
	/s/ Nicholas S. Schorsch, Jr. Nicholas S. Schorsch, Jr. Chief Executive Officer

The Notice of Internet Availability of Proxy Materials, Notice of Meeting, Proxy Statement and 2025 Annual Report to Stockholders are available free of charge at www.envisionreports.com/NYC for registered stockholders and www.edocumentview.com/NYC for beneficial holders.

TABLE OF CONTENTS

American Strategic Investment Co.

TABLE OF CONTENTS

	Page
PROXY STATEMENT		1
QUESTIONS AND ANSWERS ABOUT THE MEETING AND VOTING		2
BOARD OF DIRECTORS, EXECUTIVE OFFICERS AND CORPORATE GOVERNANCE		7
Board of Directors and Executive Officers		7
Nominees for Class III Director		8
Continuing Directors		8
Executive Officers		10
Information About the Board of Directors and its Committees		11
Leadership Structure of the Board of Directors		11
Oversight of Risk Management		11
Hedging Policy		12
Audit Committee		12
Compensation Committee		12
Nominating and Corporate Governance Committee		13
Director Independence		14
Managing Director		15
Family Relationships		15
Compensation Committee Interlocks and Insider Participation		15
Communications with the Board of Directors		15
COMPENSATION AND OTHER INFORMATION CONCERNING OFFICERS, DIRECTORS AND CERTAIN STOCKHOLDERS		16
Compensation Discussion and Analysis		16
Pay Ratio		17
Summary Compensation Table		17
Grants of Plan-Based Awards		18
Outstanding Equity Awards at Fiscal Year End		18
Option Exercises and Stock Vested		18
Potential Payments Upon Termination or Change in Control		18
Compensation Policies and Practices Related to Risk Management		19
Compensation of Directors		19
Share-Based Compensation		20
Securities Authorized for Issuance Under Equity Compensation Plans		20
Pay Versus Performance Disclosure		20
STOCK OWNERSHIP BY DIRECTORS, OFFICERS AND CERTAIN STOCKHOLDERS		23
SECTION 16(a) BENEFICIAL OWNERSHIP REPORTING COMPLIANCE		24
CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS		25
Advisor		25
Indemnification Obligations		29
Certain Conflict Resolution Procedures		29

TABLE OF CONTENTS

	Page
AUDIT COMMITTEE REPORT		30
Audit Committee		30
COMPENSATION COMMITTEE REPORT		31
Compensation Committee		31
PROPOSAL NO. 1 - ELECTION OF DIRECTORS		32
PROPOSAL NO. 2 - RATIFICATION OF APPOINTMENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM		33
Fees		33
Pre-Approval Policies and Procedures		33
PROPOSAL NO. 3 - NON-BINDING ADVISORY VOTE ON EXECUTIVE COMPENSATION		35
CODE OF ETHICS AND CORPORATE GOVERNANCE GUIDELINES		36
OTHER MATTERS PRESENTED FOR ACTION AT THE ANNUAL MEETING		36
STOCKHOLDER PROPOSALS FOR THE 2027 ANNUAL MEETING		37
Stockholder Proposals in the Proxy Statement		37
Stockholder Proposals and Nominations for Directors to Be Presented at Meetings		37

TABLE OF CONTENTS

222 Bellevue Ave.
Newport, Rhode Island 02840

PROXY STATEMENT

The accompanying proxy is solicited by and on behalf of the board of directors (the "Board of Directors" or the "Board") of American Strategic Investment Co., a Maryland corporation (the "Company"), for use at the 2026 Annual Meeting of Stockholders, including any postponement or adjournment thereof (the "Annual Meeting"), and is provided together with this proxy statement (this "Proxy Statement") and our Annual Report to Stockholders for the year ended December 31, 2025 (our "2025 Annual Report"). References in this Proxy Statement to "we," "us," "our," or like terms also refer to the Company, and references in this Proxy Statement to "you" refer to the stockholders of the Company. The mailing address of our principal executive office is 222 Bellevue Ave., Newport, Rhode Island 02840, Attention: Investor Relations. Pursuant to rules adopted by the Securities and Exchange Commission ("SEC"), the Company is providing stockholders with access to its proxy materials over the Internet. As a result, the Company is mailing a Notice Regarding Availability of Proxy Materials (the "Notice of Availability") instead of a paper copy of the proxy materials. All stockholders receiving the Notice of Availability will have the ability to access the proxy materials over the Internet and to request a paper copy by mail by following the instructions in the Notice of Availability. In addition, the proxy card contains instructions for electing to receive proxy materials over the Internet or by e-mail. Mailing of paper copies of this Notice of Annual Meeting of Stockholders and Proxy Statement will begin on or about April 23, 2026.

TABLE OF CONTENTS

QUESTIONS AND ANSWERS ABOUT THE MEETING AND VOTING

We are providing you with this Proxy Statement, which contains information about the items to be considered and voted on at the Annual Meeting. To make this information easier to understand, we have presented some of the information in a question-and-answer format.

When is the Annual Meeting and where will it be held?

The Annual Meeting will be held on June 2, 2026 commencing at 2:00 p.m. Eastern Time. The Annual Meeting will be held in a virtual meeting format only and can be accessed online at meetnow.global/ MLJAF4H. There is no physical location for the Annual Meeting. In order to attend the virtual meeting, you will need your control number. Your control number will be supplied to you via your Notice of Availability, proxy card or voting instructions form. At the Annual Meeting you will be allowed to vote your shares within the online portal, as well as to submit questions through the online portal. The online portal will open 15 minutes before the beginning of the Annual Meeting. If you have any technical disruptions or connectivity issues during the Annual Meeting, please allow for some time for the meeting website to refresh automatically, or for the meeting operator to provide updates.

If your shares are held by a broker, bank or other nominee, you must follow the instructions provided by your broker, bank or other nominee to vote your shares and you may not vote your shares in person at the meeting unless you obtain a legal proxy. If you wish to attend the Annual Meeting, you must register in advance.

To register to attend the Annual Meeting online by webcast you must submit proof of your proxy power (legal proxy) reflecting your American Strategic Investment Co. holdings along with your name and email address to Computershare. Requests for registration must be labeled as "Legal Proxy" and be received no later than 5:00 p.m., Eastern Time, on May 28, 2026 (3 business days in advance of the meeting).

You will receive a confirmation of your registration by email after we receive your registration materials.

Requests for registration should be directed to us at the following

By email

Forward the email from your broker, or attach an image of your legal proxy, to [email protected]

By mail
Computershare
COMPANY Legal Proxy
P.O. Box 43001
Providence, RI 02940-3001

Registered stockholders as of the close of business on April 10, 2026, the record date (the "Record Date") may register to participate in the Annual Meeting remotely by visiting the website www.envisionreports.com/NYC. Please have your voting instruction form or other communication containing your control number available and follow the instructions to complete your registration request.

Why did you send me these Proxy Materials?

You are receiving these materials because you owned shares of our Class A common stock, $0.01 par value per share (the "Common Stock"), as a "registered" stockholder or you held shares of Common Stock in "street name" as of the close of business on the Record Date for the Annual Meeting. This Proxy Statement contains information related to the solicitation of proxies for use at the Annual Meeting.

We had 2,692,941 shares of Common Stock issued and outstanding and entitled to vote at the Annual Meeting as of the close of business on the Record Date.

Who is soliciting my proxy?

This solicitation of proxies is made by and on behalf of our Board of Directors. Under applicable

TABLE OF CONTENTS

regulations of the SEC, each of our directors and director nominees, and certain of our officers, may solicit proxies and are "participants" in this proxy solicitation on behalf of the Board. For more information about our directors and executive officers, please see "Board of Directors, Executive Officers and Corporate Governance" beginning on page 7 of this Proxy Statement. Other than the persons described in this Proxy Statement, no regular employees of our advisor, New York City Advisors, LLC (the "Advisor"), will solicit stockholders in connection with this proxy solicitation. However, in the course of their regular duties, certain administrative personnel may be asked to perform clerical or ministerial tasks in the furtherance of this solicitation.

What is a proxy?

A proxy is a person who votes the shares of stock of another person who could not attend a meeting. The term "proxy" also refers to the proxy card or other method of appointing a proxy. By submitting your proxy to us, you are appointing Nicholas S. Schorsch, Jr. and Michael LeSanto, each of whom are executive officers of the Company, as your proxies, and you are giving them permission to vote your shares of Common Stock at the Annual Meeting.

What am I being asked to vote on at the Annual Meeting?

At the Annual Meeting, you will be asked to consider and vote upon:

•

the election of Louis P. DiPalma and Edward M. Weil, Jr. as Class III directors to serve until our 2029 annual meeting of stockholders (the "2029 Annual Meeting") and until their respective successors are duly elected and qualify;

•

the ratification of the appointment of CBIZ CPAs P.C. ("CBIZ") as the Company's independent registered public accounting firm for the year ending December 31, 2026;

•

the adoption of a non-binding advisory resolution regarding executive compensation as described herein; and

•

the transaction of such other matters as may properly come before the Annual Meeting.

Who is entitled to vote?

Anyone who is a holder of record of Common Stock as of the close of business on the Record Date or who holds a valid proxy for the Annual Meeting, is entitled to vote at the Annual Meeting. Each share of Common Stock held as of the close of business on the Record Date entitles the holder to one vote.

What is a "broker non-vote"?

A broker non-vote occurs when a broker, bank or other nominee holding shares for a beneficial owner submits a proxy but does not vote on a particular proposal because the broker or other nominee does not have discretionary voting power for that matter and has not received voting instructions from the beneficial owner. Brokers or other nominees are not allowed to exercise their voting discretion with respect to the election of directors or for the approval of other matters which the New York Stock Exchange ("NYSE") rules determine to be "non-routine," without specific instructions from the beneficial owner. Thus, beneficial owners of shares held in broker accounts are advised that, if they do not timely provide instructions to their broker, their shares will only be voted at the Annual Meeting in connection with the proposal to ratify the appointment of CBIZ, which is a "routine" matter for purposes of broker discretionary authority. Even without these instructions, the shares of stock of beneficial owners will be treated as present for the purpose of establishing a quorum if the broker votes shares on the proposal to ratify the appointment of CBIZ.

What constitutes a "quorum"?

If holders of a majority of shares of our outstanding Common Stock as of the close of business on the Record Date are present at the Annual Meeting, either in person or by proxy, we will have a quorum present, permitting the conduct of business at the Annual Meeting. Abstentions and broker non-votes, to the extent any broker non-votes exist, will be counted to determine whether a quorum is present.

TABLE OF CONTENTS

How does the Board of Directors recommend I vote on each proposal?

The Board of Directors recommends you vote:

•

"FOR" the election of Louis P. DiPalma and Edward M. Weil, Jr. as Class III directors;

•

"FOR" the ratification of the appointment of CBIZ as our independent registered public accounting firm for the year ending December 31, 2026; and

•

"FOR" the non-binding advisory resolution regarding executive compensation.

How do I vote?

Stockholders can vote in person at the meeting via webcast or by authorizing a proxy. Stockholders have the following three options for authorizing a proxy to vote their shares:

•

via the Internet at www.envisionreports.com/NYC;

•

by telephone, for automated voting (800) 652-8683 at any time prior to 11:59 p.m. Eastern Time on June 1, 2026 by following the instructions provided on the proxy card; or

•

if you requested a printed set of proxy materials, by completing, signing, dating and returning the enclosed proxy card.

For those registered stockholders with Internet access, we encourage you to authorize a proxy to vote your shares via the Internet, because it is quick, convenient and provides a cost savings to us. Authorizing a proxy to vote your shares by following the instructions on the Notice of Availability or the proxy card prior to the meeting date will ensure that your vote is recorded immediately and avoid postal delays that my cause your proxy to arrive late in which case your vote will not be counted.

If you are a registered stockholder and elect to attend the Annual Meeting, you can submit your vote during the Annual Meeting within the online portal, and any previous proxy that you authorized by following the instructions on the Notice of Availability or proxy card, will be superseded. To attend the Annual Meeting, you will need your control number.

Street Name Stockholders. If you are the beneficial owner of shares (that is, you held your shares in "street name" through an intermediary such as a broker, bank or other nominee) as of the close of business on the Record Date, you will receive instructions from your broker, bank or other nominee as to how to vote your shares or submit a proxy to have your shares voted. In most cases, you will be able to submit a proxy to vote your shares by mail or via the Internet, or possibly by telephone depending on the broker's procedures. As discussed herein, your broker, bank or other nominee may not be able to vote your shares on certain matters including the election of directors unless you provide instructions on how to vote your shares. You should instruct your broker, bank or other nominee how to vote your shares by following the directions provided by your broker, bank or other nominee.

What if I submit my proxy and then change my mind?

Registered Stockholder. If you are a registered stockholder, you have the right to change your vote or revoke your proxy at any time before the Annual Meeting by:

•

notifying our Secretary, in writing at American Strategic Investment Co., 222 Bellevue Ave., Newport, Rhode Island 02840, Attention: Secretary, prior to the Annual Meeting;

•

attending the Annual Meeting and voting in person;

•

returning another proxy card dated after your first or prior proxy card; or

•

authorizing a new proxy via the Internet to vote your shares.

Merely attending the Annual Meeting will not, by itself, revoke your proxy, you must cast a vote at the Annual Meeting following the instructions you receive upon registration. Only the most recent proxy or vote we receive before or during the Annual Meeting will be counted and all others will be discarded regardless of the method of voting.

TABLE OF CONTENTS

Street Name Stockholders. If you are the beneficial owner of your shares but not a registered stockholder, you should contact your broker, bank or other nominee to change your vote or revoke your proxy.

Will my vote make a difference?

Yes. Shares of our Common Stock are widely-held. YOUR VOTE IS VERY IMPORTANT! Your immediate response will help avoid potential delays and may save us significant additional expenses associated with soliciting stockholder votes.

What are the voting requirements for the proposals?

Proposal No. 1 - Election of Directors. The election of the nominees for director requires the affirmative vote of a plurality of all of the votes cast at a duly called meeting at which a quorum is present, in person via webcast or by proxy. There is no cumulative voting in the election of our directors. Each share may be voted for as many individuals as there are directors to be elected and for whose election the share is entitled to be voted. For purposes of this proposal, withhold votes and broker non-votes will not be counted as votes cast and will have no effect on the result of the vote, but will be considered present for quorum purposes of determining the presence of a quorum.

Proposal No. 2 - Ratification of Appointment of Independent Registered Public Accounting Firm. This proposal requires the affirmative vote of a majority of all of the votes cast at a duly called meeting at which a quorum is present. For purposes of this proposal, abstentions will not be counted as votes cast and will have no effect on the result of the vote on this proposal, although they will be considered present for the purpose of determining the presence of a quorum. Because brokers have discretionary voting authority with regard to this proposal we do not expect any broker non-votes in connection with this proposal.

Proposal No. 3 - Non-Binding Advisory Vote on Executive Compensation of our Named Executive Officers. This proposal requires the affirmative vote of a majority of all of the votes cast at a meeting at which a quorum is present. For purposes of this proposal, abstentions and broker non-votes, if any, will not be counted as votes cast and will have no effect on the result of the vote, although they will be considered present for the purpose of determining the presence of a quorum. Because this proposal is an advisory vote, the result will not be binding on the Board or the Company. Our obligation to reimburse our Advisor for amounts incurred by the Advisor for salaries, bonuses or benefits of certain of our named executive officers is governed by the terms of the advisory agreement with the Advisor, which does not expire until July 2030, and cannot be amended except with the mutual consent of the parties.

How will proxies be voted?

Shares of Common Stock represented by valid proxies will be voted at the Annual Meeting in accordance with the directions given. If the proxy card is signed and returned without any directions, the shares will be voted (1) "FOR" the election of Louis P. DiPalma and Edward M. Weil, Jr. as Class III director, to serve until our 2029 Annual Meeting and until their respective successors are duly elected and qualify, (2) "FOR" the ratification of the appointment of CBIZ as the Company's independent registered public accounting firm for the year ending December 31, 2026, and (3) "FOR" the non-binding advisory resolution regarding executive compensation.

The Board does not intend to present, and has no information indicating that others will present, any business at the Annual Meeting other than as set forth in the attached Notice of Annual Meeting of Stockholders. If other matters requiring the vote of our stockholders properly come before the Annual Meeting, the persons named in the proxy card intend to vote the proxies held by them in their discretion.

When are the stockholder proposals for the next annual meeting of stockholders due?

Stockholders interested in nominating a person for election as a director or presenting any other business for consideration at our 2027 annual meeting of stockholders (the "2027 Annual Meeting") may do so by following the procedures prescribed in our Bylaws and, in the case of proposals or nominations within

TABLE OF CONTENTS

the scope of Rule 14a-8 or Rule 14a-19 under the Securities Exchange Act of 1934, as amended (the "Exchange Act"), by following the procedures specified by those rules. For additional information, including deadlines applicable to the 2027 Annual Meeting see "Stockholder Proposals for the 2027 Annual Meeting."

Who pays the cost of this proxy solicitation?

We will pay all of the costs of soliciting on behalf of our Board of Directors. We have engaged Computershare ("Computershare") to, among other things, assist us in distributing and soliciting proxies. We expect to pay Computershare aggregate fees of approximately $30,000 to distribute proxies plus other fees and expenses for other services related to this proxy distribution, including disseminating broker search cards; distributing proxy materials; operating online and telephone voting systems; and receiving executed proxies. We will reimburse brokers and other custodians, nominees and fiduciaries for their reasonable out-of-pocket expenses to the extent they forward proxy materials to our stockholders.

Where can I find more information?

You may access, read and print copies of the proxy materials for this year's Annual Meeting, including this Proxy Statement, the Notice of Availability, the Notice of Annual Meeting of Stockholders, form of proxy card, and 2025 Annual Report, at the following websites: registered stockholders can access proxy materials at www.envisionreports.com/NYC and beneficial holders can access proxy materials at www.edocumentview.com/NYC.

Since you received a Notice of Availability, you will not receive printed copies of the proxy statement and proxy card unless you request them by following the instructions on the Notice of Availability or provided by your broker, bank or nominee. The Notice of Availability will instruct you as to how you may access and review the proxy statement and vote your proxy.

Some of your shares of Common Stock may be registered differently or held in a different account. You should vote the shares in each of your accounts by one of the methods described herein. If you mail proxy cards, please sign, date and return each proxy card to guarantee that all your shares of Common Stock are voted. The SEC has adopted a rule concerning the delivery of documents filed by us with the SEC, including proxy statements and annual reports. The rule allows us to, among other things, send a single set of any proxy statement, annual report, notices or information statement to any household at which two or more stockholders reside if they share the same address. This procedure is referred to as "Householding." This rule benefits both you and us by reducing the volume of duplicate information received at your household and helps us reduce expenses. Each stockholder subject to Householding will continue to have a separate stockholder identification number and receive a separate proxy card or voting instruction card.

We will promptly deliver, upon written or oral request, a separate copy of our 2025 Annual Report and this Proxy Statement to a stockholder at a shared address to which a single copy was previously delivered. If you have any questions about this Proxy Statement or the Annual Meeting or if you received a single set of disclosure documents for this year, but you would prefer to receive your own copy, you may direct requests for separate copies by calling our Investor Relations department at (866) 902-0063 or mail us a request to American Strategic Investment Co., 222 Bellevue Ave., Newport, Rhode Island 02840, Attention: Investor Relations. Our email address is [email protected]. Our website is www.americanstrategicinvestment.com.

We file annual, quarterly and current reports, proxy statements and other information with the SEC. You may read and copy any reports, statements or other information we file with the SEC on the website maintained by the SEC at www.sec.gov.

TABLE OF CONTENTS

BOARD OF DIRECTORS, EXECUTIVE OFFICERS AND CORPORATE GOVERNANCE

Our Board of Directors is divided into three classes of directors. Each director serves until the annual meeting of stockholders held in the third year following the year of his or her election and until his or her successor is duly elected and qualifies. At the Annual Meeting, two Class III directors will be elected to serve until the 2029 Annual Meeting and until their respective successors are duly elected and qualify. The number of directors in each class may be changed from time to time by the Board to reflect matters such as an increase or decrease in the number of directors so that each class, to the extent possible, will have the same number of directors. Our Bylaws stipulate that the number of directors may not be less than one, which is the minimum number required by the Maryland General Corporation Law (the "MGCL"), or more than 15. The number of directors on our Board is currently fixed at four persons. At any time that the number of directors comprising the Board is less than five, one director must be a managing director. A "managing director" means an individual identified by the Advisor or, in the absence of such identification, the individual then serving as chief executive officer. At any time that the number of directors comprising the Board is five or more, up to two directors shall be managing directors; provided, however, that, if only one managing director is identified by the Advisor, the Board will include one managing director. To qualify for nomination or election as a director, an individual at the time of nomination and election must meet the qualifications of an independent director or managing director, as the case may be, depending on the position for which such individual may be nominated or elected. An "independent director" means an individual who meets the qualifications of an independent director set forth in our corporate governance guidelines, as amended from time to time. Our Board is comprised of three persons who are "independent directors" and one who is a "managing director." Our corporate governance guidelines require a majority of our directors to be "independent directors" as that term is defined in the rules of the NYSE and the applicable rules of the SEC. Any director of the Company may resign at any time by delivering his or her resignation to the Board, the chairman of the Board or the secretary. Any resignation will take effect immediately upon its receipt or at such later time specified in the resignation. The acceptance of a resignation will not be necessary to make it effective unless otherwise stated in the resignation.

Board of Directors and Executive Officers

The table set forth below lists the names, ages and certain other information about each member of the Board including Mr. DiPalma and Mr. Weil. Mr. DiPalma and Mr. Weil are Class III directors with a term expiring at the Annual Meeting. Each of Mr. DiPalma and Mr. Weil has been nominated for election as a Class III director at the Annual Meeting. We have also included information regarding each of the continuing members of our Board and each of our executive officers.

Directors with Terms expiring at the
Annual Meeting/Nominee

Class

Age

Position

Director
Since

Current
Term
Expires

Expiration
of Term
for Which
Nominated

Louis P. DiPalma

III

Independent Director, Audit Committee Chair

2022

2026

2029

Edward M. Weil, Jr.

III,
Managing
Director

Director

2015

2026

2029

Continuing Directors

Nicholas Radesca

Independent Director, Compensation Committee Chair

2023

2027

Elizabeth K. Tuppeny

Lead Independent Director, Nominating and Corporate Governance Committee Chair

2014

2028

Executive Officers
(not listed above)

Nicholas S. Schorsch, Jr.

N/A

Chief Executive Officer

N/A

Michael LeSanto

N/A

Chief Financial Officer and Treasurer

N/A

TABLE OF CONTENTS

Nominees for Class III Directors

Edward M. Weil, Jr.

Edward M. Weil, Jr., a Class III director, has served as a director of the Company since 2015. Mr. Weil served as executive chairman of the Company from November 2015 to September 2023 and as chief executive officer, president and secretary of the Company, the Advisor and New York City Properties, LLC, the Company's property manager (the "Property Manager"), from March 2017 to September 2023. Mr. Weil owns a non-controlling interest in the parent of AR Global Investments, LLC ("AR Global"), which is the parent company of the Advisor and the Property Manager, since January 2016. He also has served Global Net Lease Inc. (NYSE: GNL) ("GNL") as director since January 2017, its chief executive officer since September 2023 and its president since April 2024. He also served as chairman of the board of directors of The Necessity Retail REIT, Inc. ("RTL") and as chief executive officer and president of RTL and RTL's advisor and RTL's property manager from November 2015 until their merger and internalization with NYSE-listed GNL in September 2023; and as a director of National Healthcare Properties, Inc. ("NHP") since October 2016 and as chief executive officer of NHP and its advisor and property manager from August 2018 until September 2023. From March 2021 until November 2022, he has also served as a director of G&P Acquisition Corp., a special purpose acquisition company previously listed on the NYSE that was sponsored by affiliates of AR Global.

Mr. Weil previously served in leadership positions at multiple REITs and other entities advised by affiliates of AR Global. Mr. Weil was formerly the senior vice president of sales and leasing for American Financial Realty Trust, where he was responsible for the disposition and leasing activity for a 33 million square foot portfolio of properties. Mr. Weil also previously served on the board of directors of the Real Estate Investment Securities Association (now known as ADISA) from 2012 to 2014, including as its president in 2013. Mr. Weil attended George Washington University.

Our Board of Directors believes that Mr. Weil's experience as a director or executive officer of the companies described above and his significant experience in real estate make him well qualified to serve as a member of our Board of Directors.

Louis P. DiPalma

Louis P. DiPalma, a Class III director, has served as a director of the Company since December 2022. Mr. DiPalma is a member of the Rhode Island State Senate, to which he was first elected in 2009. Mr. DiPalma's current roles as a member of the Rhode Island State Senate include: chair of the Senate Committee on Finance, member of the Senate Committee on Education, member of the Senate Committee on Artificial Intelligence and Emerging Technologies, co-chair of the Rhode Island Defense Economy Planning Joint Commission and the Joint Municipal Shared Services Commission. Mr. DiPalma is the Undersea Systems Chief Engineer at Raytheon Technologies Corporation where he has been employed since 1983 and has led teams of over one thousand engineers on engineering efforts associated with technical project planning, including budgeting, scheduling, fiscal analysis and reporting. He earned a Bachelor of Science degree in Computer Engineering from the University of Bridgeport in 1983 and a Masters in Computer Science from Brown University in 1989.

Our Board of Directors believes that Mr. DiPalma's experience in leadership positions at Raytheon and his experience serving on multiple committees in the Rhode Island State Senate makes him well qualified to serve on our Board of Directors.

The Board determined that Mr. DiPalma is "independent" as defined under the NYSE definition and applicable SEC rules. The Board appointed Mr. DiPalma to be chairman of the Company's audit committee and designated him as an "audit committee financial expert" as defined by the SEC and required by the NYSE.

Continuing Directors

Nicholas Radesca

Nicholas Radesca, a Class I director, was appointed to our Board of Directors on December 28, 2023, to fill a vacancy on the Board, and was elected at our 2024 annual meeting of stockholders held on May 29, 2024,

TABLE OF CONTENTS

to serve until the Company's 2027 annual meeting of stockholders. Mr. Radesca has decades of public company experience, including as an independent director of G&P Acquisition Corp. from January 2021 to December 2022. Mr. Radesca served as the chief financial officer of GNL, the GNL advisor and GNL property manager from January 2017 through October 2017. Mr. Radesca also served as the interim chief financial officer and treasurer of NYCR, the NYC advisor and NYCR property manager from June 2015 through November 2017. Mr. Radesca served as chief financial officer, treasurer and secretary of American Finance Trust, Inc. ("AFIN"), the AFIN advisor and the AFIN property manager from November 2015 through November 2017. He also previously served as an executive officer of AFIN from December 2014 until May 2015. Mr. Radesca joined the predecessor to AR Global in December 2012 and served as chief financial officer of AR Global and its predecessor from January 2014 through November 2017. Prior to joining the predecessor to AR Global, in December 2012, Mr. Radesca was employed by Solar Capital Management, LLC, from March 2008 to May 2012, where he served as the chief financial officer and corporate secretary for Solar Capital Ltd. and its predecessor company, and Solar Senior Capital Ltd., both of which are publicly traded business development companies. From 2006 to February 2008, Mr. Radesca served as the chief accounting officer at iStar Financial Inc. ("iStar"), a publicly traded commercial REIT, where his responsibilities included overseeing accounting, tax and SEC reporting. Prior to iStar, Mr. Radesca served in various senior accounting and financial reporting roles at Fannie Mae, Del Monte Foods Company, Providian Financial Corporation and Bank of America. Mr. Radesca has 25 years of experience in financial reporting and accounting and is a licensed certified public accountant in New York and Virginia. Mr. Radesca holds a B.S. in accounting from the New York Institute of Technology and a M.B.A. from the California State University, East Bay.

Our Board of Directors believes that Mr. Radesca's extensive background in real estate, credit, M&A and operating businesses make him well qualified to serve on our Board of Directors.

The Board determined that Mr. Radesca is "independent" as defined under the NYSE definition and applicable SEC rules. The Board appointed Mr. Radesca to serve on the Company's audit committee, compensation committee and nominating and governance committee, and to serve as the chairman of the compensation committee. The Board designated him as an "audit committee financial expert" as defined by the SEC.

Elizabeth K. Tuppeny

Elizabeth K. Tuppeny, a Class II director, has served as an independent director of the Company since March 2014, including as the lead independent director since December 2014. Ms. Tuppeny has also served as an independent director of National Healthcare Properties, Inc. ("NHP"), a public real estate investment trust (REIT), since January 2013, including as the chair of NHP's nominating and corporate governance committee since January 2016 and compensation committee since October 2024. Ms. Tuppeny has also served as an independent director of Franklin BSP Realty Trust, Inc. (NYSE: FBRT), a wholly-owned subsidiary of Franklin Templeton and a real estate finance company focused on mortgage origination and acquisition for a diversified portfolio of commercial real estate debt secured by properties located in the United States, since January 2013, including as its lead independent director since July 2016. Ms. Tuppeny has also served as independent director of Franklin BSB Real Estate Debt, Inc. Ms. Tuppeny also served as an independent director of American Realty Capital Trust IV, Inc. from May 2012 until January 2014.

As the chief executive officer and founder of Domus, Inc. ("Domus"), a full-service marketing communications agency, Ms. Tuppeny has over 30 years of experience in the branding and advertising industries and has driven business strategies for Fortune 500 companies, focused on maximizing return on investment with internal, external and brand advocacy marketing. Domus provides services to Fortune 500 companies, including Chevron, Citibank, ConAgra, Diageo, DuPont, Epson, Mattel, Merck, Merrill Lynch, Procter & Gamble, Ralph Lauren and Westinghouse. Domus' real estate clients include Ritz Carlton Residences, S&H Associate's (Tel Aviv) Parkway 22, and PMC Real Estate.

Ms. Tuppeny also founded EKT Development, LLC to pursue entertainment projects in publishing, feature film and education video games. Ms. Tuppeny served on the board of directors and executive committee of the Philadelphia Industrial Development Council, a public-private development organization,

TABLE OF CONTENTS

for three-plus years where she evaluated and approved over 500 industrial and commercial real estate transactions totaling over $1 billion that helped to attract jobs to Philadelphia, including Citizen's Bank Park and The Navy Yard.

Ms. Tuppeny has served on the boards of directors and advisory committees for the Arthur Ashe Foundation, Avenue of the Arts, Drexel Medical School, Philadelphia International Tourism Cabinet, Pennsylvania Commission for Women, Penn Relays and the Police Athletic League. Ms. Tuppeny was the recipient of the prestigious national Stevie Award as the nation's top woman entrepreneur in 2004, outperforming 13,000 entrants, and was named as a "Top Woman in Philadelphia Business" in 1996, one of the "Top 50 Women in Pennsylvania" in 2004 and as the "Businessperson of the Year" in 2003 by the Greater Philadelphia Chamber of Commerce.

Ms. Tuppeny has expertise in world-class governance best practices from her certifications from Harvard Business School's Executive Leadership program, Making Corporate Boards More Effective; the National Association of Corporate Directors' Master Class, MIT's Cybersecurity: Technology, Application and Policy, EY's Center for Board Matters and is currently completing Leverage Diversity and Inclusion for Organizational Excellence at Stanford's Graduate School of Business.

Ms. Tuppeny has taught at Temple University, taught post-graduate students Strategic Positioning and Branding at New York University, and has guest-lectured on the same topic at the University of Pennsylvania, where she received her undergraduate degree from the University of Pennsylvania's College of Arts and Sciences and The Annenberg School of Communications. Ms. Tuppeny was inaugurated into the University of Pennsylvania's Senior Honor Society and is a member of the University of Pennsylvania's Sports Hall of Fame, where she held five all-time school records.

Our Board of Directors believes that Ms. Tuppeny's extensive experience as a director of the companies described above and as chief executive officer and founder of Domus makes her well qualified to serve as a member of our Board of Directors. The Board determined that Ms. Tuppeny is "independent" as defined under the NYSE definition and applicable SEC rules.

Executive Officers

Nicholas S. Schorsch, Jr.

Nicholas Schorsch, Jr., has served as the chief executive officer of the Company since March 2025. Mr. Schorsch has spent over a decade in the real-estate, financial services, capital markets and M&A spaces as a member of the team at Bellevue Capital Partners, LLC ("Bellevue Capital"), where he has served as the Chief Operating Officer of AR Global Investments, LLC ("AR Global") since 2015. Previously, he served as President of G&P Acquisition Corp, from 2020 to 2022, the Executive Vice President at American Realty Capital Properties, from February 2014 to November 2014 and Realty Capital Securities, from March 2015 to November 2015. During Mr. Schorsch, Jr.'s career, he has focused on acquisitions, operations and operational integration of individual assets, portfolios and enterprises, having helped source over $1 billion in real-estate acquisitions in multiple asset classes, served on the investment committee for a corporate credit fund focused on middle market companies with $2.6 billion in assets under management. Additionally, Mr. Schorsch, Jr. managed a team that raised over $10 billion in retail equity for various funds, participated in over $20 billion of corporate M&A transactions, helped build an integrated financial services platform with nearly 10,000 employees servicing 2.5 million accounts with almost $225 billion in assets under management. In his career, he has overseen diligence and acquisition of concepts for the platform in the brewing and distilling, hospitality and lodging, restaurants, consumer goods, entertainment and the automotive sectors. Mr. Schorsch, Jr. has also led Bellevue Capital's technology initiatives to modernize its cloud infrastructure across its global operations and develop proprietary database systems to properly allocate platform costs among the subsidiaries of Bellevue Capital. Mr. Schorsch, Jr. is a graduate of Sarah Lawrence College, where he earned his Bachelor of Arts degree.

Michael LeSanto

Michael LeSanto has served as chief financial officer and treasurer of the Company since 2024. Mr. LeSanto joined the Company in 2020 as senior portfolio controller and was part of the Company as it

TABLE OF CONTENTS

transitioned from New York City REIT to American Strategic Investment Co. From 2021 through 2024, he served as the Company's Chief Accounting Officer. He has served in a number of senior financial roles prior to joining the Company. From 2018 through 2020, he was Director and Corporate Controller of The Predictive Index. Prior to that role he served as the Controller of Viral Gains from 2016 through 2018. From 2013 through 2016 he served as VP of Finance, North America for David Wood and Associates in San Francisco. Mr. LeSanto has a background in public accounting, working for regional firms and most recently at RSM US. He has worked in both publicly traded and private companies and has been a strategic partner in early stage start-ups as well as private equity backed organizations. He has been part of numerous capital raises from Series A through growth stage. Mr. LeSanto earned his Bachelor of Science in Accounting from Bentley University and his Masters in Accounting from McCallum Graduate School at Bentley University graduating both cum laude.

Information About the Board of Directors and its Committees

The Board of Directors is responsible for overseeing our Advisor and the management and control of our business and operations. Our current executive officers are employees of affiliates of the Advisor. We have no employees and have retained the Advisor to manage our day-to-day operations. The Advisor is under common control with AR Global. Mr. Weil, one of our directors, is the chief executive officer of AR Global and has a non-controlling interest in the parent of AR Global. Mr. Schorsch, Jr. currently serves as the chief operating officer of AR Global and is also the son of Nicholas S. Schorsch, the managing member of Bellevue Capital, which owns and controls AR Global, and beneficially owns 58.3% of the Company's common stock according to the Schedule 13D/A filed by Bellevue Capital with the SEC on January 7, 2026. See also "Stock Ownership by Directors, Officers and Certain Stockholders" and "Certain Relationships and Related Transactions."

The Board of Directors held a total of six meetings and acted by written consent or electronically on three occasions during the year ended December 31, 2025. All directors attended all of the Board meetings and all of the meetings of the Board committee on which such directors served during such period. All directors attended the 2025 Annual Meeting of Stockholders. We encourage all directors to attend our annual meetings of stockholders. The Board of Directors has a standing audit committee, compensation committee and nominating and corporate governance committee.

Leadership Structure of the Board of Directors

Mr. Schorsch, Jr. serves as our chief executive officer. As chief executive officer of the Company, Mr. Schorsch, Jr. is responsible for overseeing our day-to-day operations and business strategy. The Board of Directors believes that its leadership structure is appropriate in light of the Company's business and operating environment but may modify this structure in the future.

Ms. Tuppeny serves as the lead independent director of the Company. The Board of Directors believes that a lead independent director provides an additional measure of balance, ensures the independence of the Board of Directors, and enhances the Board of Directors to fulfill its management oversight responsibilities.

The lead independent director chairs meetings or executive sessions of the independent directors, reviews and comments on meeting agendas of the Board of Directors, represents the views of the independent directors to the Advisor, facilitates communication among the independent directors and between the Advisor and the independent directors, acts as a liaison with service providers, officers, attorneys and other directors generally between meetings, serves as a representative and speaks on behalf of the Company at external seminars, conferences, in the media and otherwise, and otherwise assumes such responsibilities as may be assigned to him or her by the Board of Directors. Consistent with current practices, the Company compensates Ms. Tuppeny for serving as lead independent director.

The Board believes that having a majority of independent, experienced directors, including a lead independent director, provides the right leadership and corporate governance structure for the Company.

Oversight of Risk Management

The Board of Directors has an active role in overseeing the management of risks applicable to the Company. The entire Board is actively involved in overseeing risk management for the Company through its

TABLE OF CONTENTS

approval of all property acquisitions and incurrence and assumption of debt and its oversight of the Company's executive officers and the Advisor. The nominating and corporate governance committee reviews all matters relating to the independence of the members of the Board of Directors and is responsible for reviewing and approving transactions with related parties, such as the Advisor, AR Global or any of their respective affiliates, and resolving other conflicts of interest. The compensation committee oversees all compensation plans, and, to the extent applicable, other compensation-related matters. The audit committee oversees our relationship with our independent registered public accounting firm, as well as management of accounting, financial, legal and regulatory risks.

Hedging Policy

Our Insider Trading Policy (as defined below) prohibits our directors, executive officers and certain designated employees from engaging in hedging, short sales, trading in publicly traded put or call options involving our securities.

Audit Committee

Our audit committee is comprised of Mr. DiPalma, Ms. Tuppeny and Mr. Radesca, each of whom is "independent," as described below, within the meaning of the applicable (1) requirements set forth in the Exchange Act and the applicable SEC rules and (2) listing standards of the NYSE. Mr. DiPalma is the chair of our audit committee. The amended and restated audit committee charter is available to any stockholder who sends a request to American Strategic Investment Co., 222 Bellevue Ave., Newport, Rhode Island 02840. Our audit committee held four meetings and acted by written consent or electronically on two occasions during the year ended December 31, 2025. All members of the audit committee attended all of the meetings while they were members of the audit committee. The amended and restated audit committee charter is also available on the Company's website at www.americanstrategicinvestment.com by clicking on "Investor Relations - Governance." The Board has determined that Mr. DiPalma, Ms. Tuppeny and Mr. Radesca are each qualified as an "audit committee financial expert" as defined in Item 407(d)(5) of Regulation S-K and the rules and regulations of the SEC.

The audit committee, in performing its duties, monitors:

•

our financial reporting process;

•

the integrity of our financial statements;

•

compliance with legal and regulatory requirements;

•

the independence and qualifications of our independent registered public accounting firm and internal auditors, as applicable; and

•

the performance of our independent registered public accounting firm and internal auditors, as applicable.

The audit committee's report on our financial statements for the year ended December 31, 2025 is discussed below under the heading "Audit Committee Report."

Compensation Committee

The compensation committee is comprised of Ms. Tuppeny and Mr. Radesca, each of whom is "independent," as described below, within the meaning of the applicable (1) requirements set forth in SEC rules and (2) listing standards of the NYSE. Each of Ms. Tuppeny and Mr. Radesca is a non-employee director within the meaning of the Exchange Act. Mr. Radesca is the chair of our compensation committee. Our compensation committee did not hold any meetings but acted by written consent or electronically on one occasion during the year ended December 31, 2025. The compensation committee charter is available to any stockholder who sends a request to American Strategic Investment Co., 222 Bellevue Ave., Newport, Rhode Island 02840. The compensation committee charter is also available on the Company's website at www.americanstrategicinvestment.com by clicking on "Investor Relations - Governance." The principal functions of the compensation committee are to:

TABLE OF CONTENTS

•

approve and evaluate all compensation plans, policies and programs, if any, as they affect our executive officers;

•

review and oversee the Company's annual process, if any, for evaluating the performance of our executive officers;

•

oversee our equity incentive plans, including, without limitation, the issuance of stock options, restricted shares of Common Stock, restricted stock units in respect of shares of Common Stock ("RSUs"), dividend equivalent shares and other equity-based awards;

•

assist the Board of Directors and the chairman in overseeing the development of executive succession plans, if any; and

•

determine from time to time the remuneration for our non-executive directors.

The compensation committee administers our equity plan for the Advisor (the "Advisor Plan") and our equity plan for individuals (the "Individual Plan" and together with the Advisor Plan the "2020 Equity Plan"), which were adopted effective at the listing of the Common Stock on the NYSE on August 18, 2020 (the "Listing"). See "Compensation and Other Information Concerning Officers, Directors and Certain Stockholders - Share-Based Compensation."

The compensation committee is responsible for approving and administering all grants of awards to our executive officers. In carrying out its responsibilities, our compensation committee may delegate any or all of its responsibilities to a subcommittee or any other person to the extent consistent with our charter, our Bylaws, our corporate governance guidelines and any other applicable laws, rules and regulations, including the NYSE rules. In March 2022, the compensation committee delegated authority to our chief executive officer to award up to 200,000 restricted shares to employees of the Advisor or its affiliates who are involved in providing services to us, including our chief financial officer, subject to certain limits and restrictions imposed by the compensation committee. The compensation committee remains responsible for approving and administering all grants of awards to our chief financial officer, including any award of restricted shares recommended by our chief executive officer. No awards under the 2020 Equity Plan may be made pursuant to this delegation of authority to anyone who is also a partner, member or equity owner of the parent of the Advisor.

Nominating and Corporate Governance Committee

The nominating and corporate governance committee is comprised of Ms. Tuppeny and Mr. Radesca, each of whom is "independent," as described below, within the meaning of the applicable listing standards of the NYSE and the SEC. Ms. Tuppeny is the chair of our nominating and corporate governance committee. Our nominating and corporate governance committee did not hold any meetings but acted by written consent or electronically on one occasion during the year ended December 31, 2025. The nominating and corporate governance committee charter and our corporate governance guidelines are available to any stockholder who sends a request to American Strategic Investment Co., 222 Bellevue Ave., Newport, Rhode Island 02840. The nominating and corporate committee charter and our corporate governance guidelines are also available on the Company's website at www.americanstrategicinvestment.com by clicking on "Investor Relations - Governance." The nominating and corporate governance committee is responsible for the following:

•

providing counsel to the Board of Directors with respect to the organization, function and composition of the Board of Directors and its committees;

•

overseeing the self-evaluation of the Board of Directors and, if any, the Board's evaluation of management;

•

periodically reviewing and, if appropriate, recommending to the Board of Directors changes to our corporate governance policies and procedures;

•

identifying and recommending to the Board of Directors potential director candidates for nomination; and

•

assisting the Board in connection with related party transactions.

TABLE OF CONTENTS

In evaluating directors for nomination to the Board and to serve as members of each committee of the Board, the nominating and corporate governance committee considers the applicable requirements for members of committees of boards of directors under the Exchange Act, NYSE rules, the Company's corporate governance guidelines and the charter of the applicable committee and may consider such other factors or criteria as the nominating and corporate governance committee deems appropriate. For purposes of recommending any nominee, the nominating and corporate governance committee may consider all criteria that it deems appropriate, which may include, without limitation:

•

personal and professional integrity, ethics and values;

•

experience in corporate management, such as serving as an officer or former officer of a publicly held company, and a general understanding of marketing, finance and other elements relevant to the success of a publicly held company in today's business environment;

•

experience in the Company's industry and with relevant social policy concerns;

•

experience as a board member of another publicly held company;

•

expertise and experience in an area of the Company's operations;

•

diversity of both background and experience;

•

practical and mature business judgment, including ability to make independent analytical inquiries;

•

the nature of and time involved in a director's service on other boards or committees; and

•

with respect to any person already serving as a director, the director's past attendance at meetings and participation in and contribution to the activities of the board.

The nominating and corporate governance committee evaluates each individual nominee in the context of the Board as a whole, with the objective of assembling a group that can best advance the success of the business and exercise judgment using its diversity of experience. The Board of Directors believes that diversity is an important attribute of the members who comprise our Board of Directors and that the members should represent an array of backgrounds and experiences.

Except for specific requirements set forth in our Bylaws, the nominating and corporate governance committee has not adopted a specific policy regarding the consideration of director nominees recommended to our nominating and corporate governance committee by stockholders. Stockholders who would like to propose an independent director candidate for the consideration of the Board of Directors may do so by following the procedures under the section entitled "Stockholder Proposals for the 2027 Annual Meeting - Stockholder Proposals and Nominations for Directors to Be Presented at Meetings."

For all related party transactions, the nominating and corporate governance committee has the authority to:

•

review and evaluate the terms and conditions, and determine the advisability, of the transaction;

•

negotiate the terms and conditions of the transaction, and, if the nominating and corporate governance committee deems appropriate, but subject to the limitations of applicable law, approve the execution and delivery of documents in connection with that transaction on our behalf;

•

determine whether the transaction is in the best interests of the Company; and

•

recommend to the Board of Directors what action, if any should be taken by the Board of Directors with respect to the transaction.

The nominating and corporate governance committee also has the authority to review, on a quarterly basis, the services provided by the Advisor, the reasonableness of the fees and expenses of the Advisor and its affiliates, as well as related matters.

Director Independence

The Board of Directors has currently set the number of directors at four. As required by the NYSE rules, a majority of our directors must be "independent." The Board of Directors has considered the independence

TABLE OF CONTENTS

of each director and nominee for election as a director in accordance with the elements of independence set forth in the listing standards of the NYSE, the Exchange Act and applicable SEC rules. Based upon information provided by each director, the nominating and corporate governance committee and the Board of Directors have each affirmatively determined that each of Ms. Tuppeny, Mr. Radesca and Mr. DiPalma have no material relationship with the Company (either directly or as a partner, stockholder or officer of an organization that has a relationship with the Company) other than as a director of the Company and is "independent" within the meaning of the applicable listing standards of the NYSE as well as the requirements set forth in the Exchange Act and applicable SEC rules.

Managing Director

As described herein, our Bylaws require, among other things, that at any time the number of directors comprising the Board is less than five, one director must be a "managing director." If at any time the number of directors comprising the Board is five or more, up to two directors must be "managing directors," provided, however, that if only one managing director is identified by the Advisor, the Board will include one managing director. The term "managing director" is defined under the Bylaws as an individual identified by the Advisor or, if not identified, the individual serving as the Company's chief executive officer. Mr. Weil is identified by the Advisor as a managing director.

Family Relationships

There are no familial relationships between any of our directors and executive officers.

Compensation Committee Interlocks and Insider Participation

No member of the compensation committee is or ever has been an officer or employee of the Company and no member of the compensation committee had any relationships during 2025 requiring disclosure by us under the SEC's rules requiring disclosure of certain relationships and related-party transactions. No executive officer serves as a member of a board of trustees or compensation committee, or other committee serving an equivalent function, of any other entity that has one or more of its executive officers serving as a member of the board or compensation committee. Accordingly, the fiscal year ended December 31, 2025 there were no interlocks with other companies within the meaning of the SEC's proxy rules.

Communications with the Board of Directors

Any interested parties (including the Company's stockholders) may communicate with the Board of Directors by sending written communications in care of American Strategic Investment Co., 222 Bellevue Ave., Newport, Rhode Island 02840, Attention: Secretary. The Secretary will deliver all appropriate communications to the Board of Directors no later than the next regularly scheduled meeting of the Board. If the Board modifies this process, the revised process will be posted on the Company's website, www.americanstrategicinvestment.com.

TABLE OF CONTENTS

COMPENSATION AND OTHER INFORMATION CONCERNING OFFICERS,
DIRECTORS AND CERTAIN STOCKHOLDERS

Compensation Discussion and Analysis

Overview

We are an externally managed Maryland corporation and do not have any employees. We do not employ our named executive officers ("NEOs"), have agreements with them regarding their compensation or otherwise determine the compensation earned by, or paid to, them with the exception of awards to our NEOs under the 2020 Equity Plan. Our Advisor manages our day-to-day business with the assistance of our Property Manager, and affiliates of the Advisor employ the persons who provide these services, including our NEOs. We pay the Advisor and the Property Manager certain fees and reimburse them for certain expenses as required by the terms of our agreements with them. For further details regarding our arrangements with the Advisor, the Property Manager and their affiliates, see "Certain Relationships and Related Transactions."

AR Global, the parent company of the Advisor, determines the salaries, bonuses and other benefits earned by, or paid to, our NEOs. Our advisory agreement does not require our NEOs to dedicate a specific amount of time to fulfill their obligations or those of the Advisor and its affiliates or specify an amount or percentage of the amounts we pay to the Advisor or its affiliates that must be allocated to compensating our NEOs. While Mr. Schorsch, our chief executive officer, may, in his capacity as the Chief Operating Officer of AR Global, participate in AR Global's process for determining the compensation earned by, or paid to, our NEOs by the Advisor or its affiliates, but neither our Board nor our compensation committee is involved with, or consulted regarding, this process. We are required by the terms of our advisory agreement to reimburse the Advisor for salaries, wages (including bonuses) and benefits of certain of our NEOs, subject to certain limits described in more detail below.

Expense Reimbursements

We are required by the terms of our advisory agreement to reimburse the Advisor for salaries, wages (including bonuses) and benefits of employees of the Advisor or its affiliates involved in providing services to us, subject to certain limits. Specifically, the aggregate amount of all reimbursements for salaries, wages and benefits for employees of the Advisor or its affiliates (including our executive officers) must be comparable to market rates and reimbursements may not exceed, in any fiscal year, the lesser of (a) $2,971,969, and (b) if the amount actually paid or allocated by us with respect to the assets we have acquired plus all cash and cash equivalents, marketable securities and other tangible assets held and recorded on our balance sheet of the Company is equal to or greater than $1.25 billion as of the last day of the fiscal year, that amount multiplied by 0.30% (the "Advisor Employee Compensation Limit"). The Advisor Employee Compensation Limit will be further increased by an annual cost of living adjustment equal to the Advisor Employee Compensation Limit (as determined above) multiplied by the greater of (x) 3.0% and (y) the Consumer Price Index for the prior year ended December 31st.

Other Compensation

The compensation committee is responsible for approving and evaluating all compensation plans, policies and programs affecting our executive officers including any compensation plans, policies and programs we may adopt in the future. The compensation committee must also approve any awards granted under these plans to our NEOs. An aggregate of 19,998 restricted shares were granted to our NEOs during the year ended December 31, 2025.

During the year ended December 31, 2025, we issued 43,427 restricted shares to employees of the Advisor (including our executive officers) under the Individual Plan.

In 2020, FTI Consulting, Inc. ("FTI") was engaged by the Company to make recommendations to the Board and the compensation committee on the 2021 OPP. Neither FTI nor any other compensation consultant played any role on any matters related to the Company's NEOs during 2025 or any prior period.

TABLE OF CONTENTS

Clawback Policy

The Company maintains a Clawback Policy, which is designed to comply with Section 10D-1 of the Exchange Act and the applicable listing standards of the NYSE. The Clawback Policy requires the Company to recoup any erroneously awarded incentive-based compensation received by certain executives, including each NEO, in the event the Company is required to prepare an accounting restatement due to material noncompliance with any financial reporting requirement under the federal securities laws. The Clawback Policy generally applies to all incentive-based compensation received by a covered executive during the three completed fiscal years immediately preceding the date that the Company is required to prepare a restatement after the policy's effective date. The Clawback Policy is filed as an exhibit to the Company's Annual Report on Form 10-K for the year ended December 31, 2025.

Pay Ratio

We have not included a ratio of the compensation of our chief executive officer to our median employee because we do not have any employees.

Summary Compensation Table

The following table summarizes the annual compensation received by our NEOs for the fiscal years ended December 31, 2025 and 2024:

Name and Principal Position	Year		Salary ($)(1)			Bonus ($)(1)			Stock Awards ($)(2)			All Other Compensation ($)			Total ($)
Nicholas S. Schorsch, Jr. Chief Executive Officer		2025		$	356,669		$	298,949		$	199,200		$	51,229(3)		$	906,047
Michael Anderson, Former Chief Executive Officer*		2025		$	0		$	138,536		$	0		$	36,719(4)		$	175,255
Michael Anderson, Former Chief Executive Officer*		2024		$	272,931		$	173,077		$	90,800		$	7,771(4)		$	544,579
Joseph Marnikovic Former Chief Financial Officer**		2024		$	56,498		$	-		$	-		$	8,475(5)		$	64,793
Michael LeSanto Chief Financial Officer		2025		$	250,000		$	35,000		$	59,760		$	20,516(6)		$	365,276
Michael LeSanto Chief Financial Officer		2024		$	234,173		$	35,000		$	39,725		$	33,479(6)		$	342,377

Mr. Anderson served as the Company's Chief Executive Officer from September 2023 until his resignation effective as of March 19, 2025.

Mr. Marnikovic served as the Company's Chief Financial Officer from September 2023 until his resignation effective as of April 4, 2024.

(1)

Represents the allocable share of salary and bonus paid by the Advisor or its affiliates during the fiscal years ended December 31, 2025 and 2024 that was reimbursed by the Company required by the terms of its advisory agreement.

(2)

Value of awards of restricted shares calculated in accordance with FASB ASC Topic 718. All assumptions made in the valuations are contained and described in Note 12 to the financial statements in the Company's Annual Report on Form 10-K for the year ended December 31, 2025 (the "2025 10-K").

(3)

Represents the allocable share of certain expenses incurred by the Advisor or its affiliates with respect to Mr. Schorsch that was reimbursed by the Company pursuant to its advisory agreement as follows: (x) with respect to the year ended December 31, 2025 (i) $6,027 for payroll taxes and (ii) $2,077 for matching contributions to Mr. Schorsch's 401(k).

(4)

Represents the allocable share of certain expenses incurred by the Advisor or its affiliates with respect to Mr. Anderson that was reimbursed by the Company pursuant to its advisory agreement as follows: (x) with respect to the year ended December 31, 2025 (i) $4,619 for payroll taxes and (ii) $0 for matching contributions to Mr. Anderson's 401(k) and (y) with respect to the year ended December 31, 2024, (i) $9,671 for payroll taxes and (ii) $13,800 for matching contributions to Mr. Anderson's 401(k).

TABLE OF CONTENTS

(5)

Represents the allocable share of certain expenses incurred by the Advisor or its affiliates with respect to Mr. Marnikovic that was reimbursed by the Company pursuant to its advisory agreement as follows: (x) $3,344 for payroll taxes and (y) $13,800 for matching contributions to Mr. Marnikovic's 401(k).

(6)

Represents the allocable share of certain expenses incurred by the Advisor or its affiliates with respect to Mr. LeSanto that was reimbursed by the Company pursuant to its advisory agreement as follows: (x) with respect to the year ended December 31, 2025, $5,779 for payroll taxes and (y) with respect to the year ended December 31, 2024, $3,397 for payroll taxes.

Grants of Plan-Based Awards

An aggregate of 26,000 restricted shares were granted under the Individual Plan during the fiscal year ended December 31, 2025 to our NEOs.

Policies and Practices Related to the Grant of Certain Equity Awards

In response to Item 402(x)(1) of Regulation S-K, we have not granted new awards of stock options, stock appreciation rights, or similar option-like instruments within four business days before or one business day after the release of a Quarterly Report on Form 10-Q, Annual Report on Form 10-K, or Current Report on Form 8-K that discloses material nonpublic information. Accordingly, we have no specific policy or practice on the timing of awards of such options in relation to the disclosure of material nonpublic information by us. In the event that we determine to grant new awards of such options, the Board will evaluate the appropriate steps to take in relation to the foregoing.

Outstanding Equity Awards at Fiscal Year End

The following table sets forth certain information with respect to all outstanding equity-based awards held at the end of the fiscal year ended December 31, 2025 by our NEOs:

Name	Number of Restricted Shares That Have Not Vested (#)		Market Value of Restricted Shares That Have Not Vested ($)(1)
Nicholas S. Schorsch, Jr.		29,214(2)		$	242,184
Michael LeSanto		9,369(3)		$	77,669

(1)

Based on $8.29 per share, the closing price of our Common Stock on December 31, 2025.

(2)

These restricted shares include: (i) 405 shares granted on April 25, 2022, with vesting in 25% increments on each of the first four anniversaries of the grant date, (ii) 1,309 shares granted on October 4, 2023, with vesting in 25% increments on each of the first four anniversaries commencing on October 4, 2024, (iii) 7,500 shares granted on June 18, 2024, with vesting in 25% increments on each of the first four anniversaries commencing on May 22, 2025, and (iv) 20,000 shares granted on June 26, 2025, with vesting in 25% increments on each of the first four anniversaries commenting on June 26, 2026.

(3)

These restricted shares include: (i) 36 shares granted on April 25, 2022, with vesting in 25% increments on each of the first four anniversaries of the grant date, (ii) 52 shares granted on October 4, 2023, with vesting in 25% increments on each of the first four anniversaries commencing on October 4, 2024, (iii) 4,375 shares granted on June 18, 2024, with vesting in 25% increments on each of the first four anniversaries commencing on May 22, 2025, and (iv) 6,000 shares granted on June 26, 2025, with vesting in 25% increments on each of the first four anniversaries commenting on June 26, 2026.

Option Exercises and Stock Vested

During the year ended December 31, 2025, 1,158 shares with a fair value of $12,526.23 previously granted to Mr. LeSanto vested.

Potential Payments Upon Termination or Change in Control

There are no contractual arrangements with the Company's "named executive officers" regarding any potential payments upon termination or change of control.

TABLE OF CONTENTS

Compensation Policies and Practices Related to Risk Management

The compensation committee has determined that none of the Company's compensation policies and practices create any risks that are reasonably likely to have a material adverse effect on the Company.

Compensation of Directors

We pay our independent directors the fees described below. We do not pay compensation for services rendered by persons who serve as directors and are also employees of the Company, the Advisor or any of their affiliates. We reimburse all of our directors for the reasonable out-of-pocket expenses incurred in connection with attending board or committee meetings.

We pay our independent directors a yearly retainer of $30,000 and an additional yearly retainer of $55,000 for the lead independent director; $2,000 for each meeting of the Board or any committee attended by the directors ($2,500 for attendance by the chairperson of the audit committee at each meeting of the audit committee) and $1,500 for each meeting attended via telephone; $750 per transaction reviewed and voted upon electronically up to a maximum of $2,250 for three or more transactions reviewed and voted upon per electronic vote. If there are a Board meeting and one or more committee meetings in one day, the director's fees may not exceed $2,500 ($3,000 for the chairperson of the audit committee if there is a meeting of such committee). We may issue shares of Common Stock in lieu of cash to pay fees earned by our directors, at each director's election. The shares of Common Stock issued are not subject to vesting provisions because these payments, in lieu of cash, are related to fees earned for services performed.

We award each independent director restricted shares with a market value of $65,000 determined at the time of issuance after each annual meeting of stockholders. The restricted shares vest over a five-year period on each anniversary of the issuance in increments of 20% per annum.

We also pay each independent director for each external seminar, conference, panel, forum or other industry-related event attended in person and in which the independent director actively participates, solely in such person's capacity as an independent director of the Company, in the following amounts:

•

$2,500 for each day of an external seminar, conference, panel, forum or other industry-related event that does not exceed four hours, or

•

$5,000 for each day of an external seminar, conference, panel, forum or other industry-related event that exceeds four hours.

In either of the above cases, we will reimburse, to the extent not otherwise reimbursed, an independent director's reasonable expenses associated with attending external seminars, conferences, panels, forums or other industry-related events. An independent director cannot be paid or reimbursed for attendance at a single external seminar, conference, panel, forum or other industry-related event by us and another company for which he or she is a director.

The following table sets forth information regarding compensation of our directors paid during the year ended December 31, 2025:

Name	Fees Paid in Cash ($)			Stock Awards ($)(1)			Option Awards ($)			Non-Equity Incentive Plan Compensation ($)			Changes in Pension Value and Nonqualified Deferred Compensation Earnings ($)			All Other Compensation ($)			Total Compensation ($)
Edward M. Weil, Jr.		$	-		$	-		$	-		$	-		$	-		$	-			-
Elizabeth K. Tuppeny		$	107,750		$	64,327			-			-			-		$	-		$	172,077
Nicholas Radesca		$	52,750		$	64,327			-			-			-		$	-		$	117,077
Louis P. DiPalma		$	53,250		$	64,327		$	-		$	-		$	-		$	-		$	117,577

(1)

Value of awards of restricted shares calculated based on their grant date fair value computed in accordance with FASB ASC Topic 718. All assumptions made in the valuations are contained and

TABLE OF CONTENTS

described in Note 12 to the financial statements in our 2025 10-K. Awards vest annually over a five-year period in equal installments. As of December 31, 2025, Ms. Tuppeny held 17,706 unvested restricted shares, Mr. DiPalma held 17,541 unvested restricted shares and Mr. Radesca held 12,324 unvested restricted shares.

Share-Based Compensation

The Advisor Plan is substantially similar to the Individual Plan, except with respect to the eligible participants. Awards under the Individual Plan may be made to the Company's directors, officers and employees (if the Company ever has employees), employees, officers and directors of the Advisor and as a general matter, employees and consultants of affiliates of the Advisor that provide services to the Company. Awards under the Advisor Plan may only be granted to the Advisor and its affiliates.

Under the 2020 Equity Plan, the Company may award RSUs, stock options, stock appreciation rights, stock awards, LTIP Units and other equity awards. The 2020 Equity Plan has a term of ten years, expiring August 18, 2030. The number of shares of the Company's capital stock that may be issued or subject to awards under the 2020 Equity Plan, in the aggregate, is equal to 20.0% of the outstanding shares of Common Stock on a fully diluted basis at any time. Shares subject to awards under the Individual Plan reduce the number of shares available for awards under the Advisor Plan on a one-for-one basis and vice versa.

Securities Authorized for Issuance Under Equity Compensation Plans

Plan Category	Number of Securities to be Issued Upon Exercise of Outstanding Options, Warrants, and Rights (a)		Weighted- Average Exercise Price of Outstanding Options, Warrants and Rights (b)		Number of Securities Remaining Available For Future Issuance Under Equity Compensation Plans (Excluding Securities Reflected in Column (a) (c)
Equity Compensation Plans approved by security holders		-		-		-
Equity Compensation Plans not approved by security holders		-		-		303,916
Total		-		-		303,916

(1)

The total number of shares granted as awards under the 2020 Equity Plan may not exceed 20.0% of our outstanding shares of Common Stock on a fully diluted basis at any time. As of December 31, 2025, we had 2,701,332 shares of our Common Stock issued and outstanding on a fully diluted basis, and 162,642 shares of our Common Stock had been issued under or were subject to awards under the 2020 Equity Plan.

Pay Versus Performance Disclosure

As required by Item 402(v) of Regulation S-K, which was mandated by Section 953(a) of the Dodd-Frank Act, we are providing the following information about the relationship between "compensation actually paid" to our principal executive officers or "PEOs" and "compensation actually paid" to our non-PEO NEOs (our only other NEOs who are not PEOs) and the financial performance of the Company during the years ended December 31, 2025, 2024 and 2023, respectively, in each case calculated in a manner consistent with SEC rules.

Year			Summary Compensation Table Total for PEO(1)						Compensation Actually Paid to PEO(1)(3)						Summary Compensation Table Total for PEO(2)						Compensation Actually Paid to PEO(2)(3)						Average Summary Compensation Table Total for Non-PEO NEOs(3)(4)						Average Compensation Actually Paid to Non-PEO NEOs(3)
2025					-						-					$	906,047					$	909,543					$	365,276					$	371,993

TABLE OF CONTENTS

Year	Summary Compensation Table Total for PEO(1)			Compensation Actually Paid to PEO(1)(3)			Summary Compensation Table Total for PEO(2)			Compensation Actually Paid to PEO(2)(3)			Average Summary Compensation Table Total for Non-PEO NEOs(3)(4)			Average Compensation Actually Paid to Non-PEO NEOs(3)
2024			-			-		$	544,579		$	538,486.12		$	203,675		$	201,171
2023		$	-		$	-		$	129,618		$	129,618		$	117,024		$	110,586

(1)

Edward M. Weil, Jr is the PEO reflected in these columns for fiscal year ended December 31, 2023.

(2)

Michael Anderson is the PEO reflected in these columns for fiscal years ended December 31, 2024 and 2023.

(3)

Compensation actually paid or "CAP" to our PEO and Non-PEO NEO is calculated based on the "Total Compensation" reported in the Summary Compensation Table above and in the Proxy Statement on Schedule 14A filed with the SEC on April 17, 2025 with respect to the 2025 annual meeting of stockholders, adjusted to exclude and include certain items in accordance with Item 402(v) of Regulation S-K as follows. To arrive at the Compensation actually paid to Mr. Schorsch of $909,543, $199,200, the fair value of his stock awards granted in 2025, was deducted from the total compensation received as set forth in the "Summary Compensation Table" and the following additions were made: (i) $165,800, representing the fair value of his 2025 stock awards at December 31, 2025; (ii) -$32,103, representing the change in fair value of his unvested stock awards at December 31, 2025 compared to the end of the prior fiscal year; and (iii) -$4,794, representing the change in fair value of awards that vested during fiscal year 2024 at the vesting date compared to the end of the prior fiscal year.

(4)

Christopher J. Masterson and Joseph Marnikovic are the non-PEO NEOs reflected in these columns for the fiscal years ended December 31, 2023 and 2022, and Joseph Marnikovic and Michael LeSanto are the non-PEO NEOs reflected in these columns for the fiscal year ended December 31, 2024 and Michael LeSanto is the non-PEO NEOs reflected in these columns for the fiscal year ended December 31, 2025. Mr. Masterson was the Company's chief financial officer, treasurer and secretary until September 2023, and Mr. Marnikovic was the Company's chief financial officer from September 2023 until his resignation effective as of April 4, 2024.

Average Non-PEO NEOs SCT Total to CAP Reconciliation

							Additions to SCT(2)
Fiscal Year	Summary Compensation Table ("SCT") Total			Deductions from SCT(1)			Fair Value of Current Year Equity Awards			Change in Value of Prior Years' Awards Unvested			Change in Value of Prior Years' Awards that Vested			Deductions for Forfeited Awards			CAP(3)
2025		$	365,276		$	59,760		$	49,740		$	10,517		$	6,220		$	-		$	371,993
2024		$	203,675		$	39,725		$	37,144		$	42		$	35		$	-		$	201,171
2023		$	117,024		$	-		$	-		$	-		$	(464)		$	5,974		$	110,586

(1)

Represents the grant date fair value of equity-based awards granted each year. The fair values of equity compensation, including such amounts described in the tables above, are calculated in accordance with FASB ASC Topic 718. All assumptions made in the valuations are contained and described in Note 12 to the Company's financial statements for fiscal year 2025 contained in our 2025 10-K. The amounts shown in the table reflect the total fair value on the date of grant and do not necessarily reflect the actual value, if any, that may be realized by the NEOs.

(2)

We did not report a change in pension value for any of the years reflected in this table because the Company does not maintain a defined benefit or actuarial pension plan and therefore a deduction from SCT related to such pension plans is not needed.

TABLE OF CONTENTS

(3)

Reflects the value of equity calculated in accordance with the SEC methodology for determining CAP for each year shown. The fair values of equity compensation, including such amounts described in the tables above, are calculated in accordance with FASB ASC Topic 718. All assumptions made in the valuations are contained and described in Note 12 to the Company's financial statements for fiscal year 2025 contained in our 2025 10-K. The amounts shown in the table reflect the total fair value on the applicable date(s) listed in the table above, and do not necessarily reflect the actual value, if any, that may be realized by the PEO.

TABLE OF CONTENTS

STOCK OWNERSHIP BY DIRECTORS, OFFICERS AND CERTAIN STOCKHOLDERS

The following table sets forth information regarding the beneficial ownership of shares of Common Stock as of the close of business on the Record Date, in each case including shares of Common Stock which may be acquired by such persons within 60 days, by:

•

each person known by the Company to be the beneficial owner of more than 5% of the outstanding shares of Common Stock based solely upon the amounts and percentages contained in the public filings of such persons;

•

each of the Company's NEOs and directors; and

•

all of the Company's executive officers and directors as a group.

Common Stock

Beneficial Owner(1)

Number of Shares
Beneficially
Owned

Percent of
Class

Bellevue Capital Partners, LLC and its affiliates(3)(4)

1,568,988

58.3%

Edward M. Weil, Jr.(5)

109

Elizabeth K. Tuppeny(6)

25,697

Louis P. DiPalma(6)

24,313

Nicholas Radesca

13,738

Nicholas S. Schorsch, Jr.

32,774

1.2%

Michael LeSanto

10,186

All directors and executive officers as a group (six persons)

106,817

Less than 1%.

(1)

Unless otherwise indicated, the business address of each individual or entity listed in the table is 222 Bellevue Ave., Newport, Rhode Island 02840. Unless otherwise indicated, the individual or entity listed has sole voting and investment power over the shares listed.

(3)

Includes the shares beneficially owned by Nicholas S. Schorsch, the sole managing member of Bellevue Capital Partners, LLC ("Bellevue Capital") and ultimate controlling person of New York City Advisors, LLC, and excludes the shares beneficially owned by Mr. Weil. Bellevue Capital is the sole member of AR Global, who is the sole member of American Realty Capital III, LLC ("ARC III"). ARC III is the sole member of New York City Special Limited Partnership, LLC ("NY Special"), who is the sole member of New York City Advisors, LLC ("Advisor"). The business address of Bellevue Capital and its managing member and affiliates is 222 Bellevue Avenue, Newport, Rhode Island 02840. Bellevue Capital's managing member shares voting and dispositive power over 1,568,988 shares, Bellevue Capital shares voting and dispositive power over 1,568,988 shares, and AR Global, ARC III, NY Special and Advisors each share voting and dispositive power over 520,666 shares. The information contained herein with respect to Bellevue Capital, its managing member and other affiliates is based solely on the Amendment No. 22 to the Schedule 13D filed by Bellevue Capital and its affiliates with the SEC on January 7, 2026.

(4)

In connection with our rights offering which ("Rights Offering"), our board waived the existing limit imposed on purchases by Bellevue and its affiliates including future issuances of Common Stock issued in lieu of the Company paying cash to the Advisor for asset management services. Bellevue Capital, the Advisor and other affiliates or person related to Bellevue Capital have granted an irrevocable proxy to the Company pursuant to which the Company has the right to vote any shares owned by these persons or entities in excess of 34.9% of the Company's outstanding shares of Common Stock in the same proportion as all other shares voted by the Company's stockholders. Accordingly, the Company will vote 22.8% of the shares beneficially owned by Bellevue Capital and its affiliates in the same proportion as all other shares voted by the Company's stockholders at the Annual Meeting.

(5)

Mr. Weil, our chairman, has a non-controlling interest in the parent of AR Global but Mr. Weil does not have direct or indirect voting or investment power over any shares that AR Global or the parent of AR Global may own. Mr. Weil disclaims beneficial ownership of these shares. Accordingly, the shares

TABLE OF CONTENTS

included as beneficially owned by Mr. Weil do not include the approximately 34,419 shares of Common Stock that are directly or indirectly beneficially owned by AR Global or the 876 shares of Common Stock that are directly or indirectly beneficially owned by the parent of AR Global.

(6)

Includes unvested restricted shares. As of December 31, 2025, Ms. Tuppeny held 17,706 unvested restricted shares and Mr. DiPalma held 17,541 unvested restricted shares and Mr. Radesca held 12,324 unvested restricted shares.

SECTION 16(a) BENEFICIAL OWNERSHIP REPORTING COMPLIANCE

Delinquent Section 16(a) Reports

Section 16(a) of the Exchange Act requires our directors, executive officers and persons who beneficially own more than 10% of a registered class of our equity securities to file with the SEC reports of ownership of, and transactions in, our equity securities. To our knowledge, based solely on a review of copies of such reports that we received, our records and written representations received from our directors, executive officers and certain of those persons who own greater than 10% of any class of our equity securities, for the year ended December 31, 2025, all applicable Section 16(a) filing requirements were complied with on a timely basis, except that Mr. LeSanto inadvertently filed (i) one Form 4 late on May 12, 2025, reporting one transaction that occurred on April 25, 2025, and (ii) one Form 4 late on May 28, 2025, reporting one transaction that occurred on May 22, 2025.

TABLE OF CONTENTS

CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS

Edward M. Weil, Jr., one of our directors, also is the chief executive officer, president and secretary of the Property Manager. Michael Anderson, our former chief executive officer, is also senior vice president and general counsel of the Advisor. Mr. Schorsch, Jr., our chief executive officer, is also the chief operating officer of AR Global, which controls the Advisor and the Property Manager. Mr. Schorsch, Jr. is also the son of Nicholas S. Schorsch, the managing member of Bellevue Capital, which owns and controls AR Global, and beneficially owns 58.3% of our Common Stock according to the Schedule 13D/A filed by Bellevue Capital with the SEC on January 7, 2026. AR Global indirectly owns all of the membership interests. The Property Manager is owned and controlled directly or indirectly by AR Global. Mr. Weil, one of our directors, has a non-controlling interest in the parent of AR Global.

Advisor

The Advisor manages our day-to-day operations pursuant to the advisory agreement with the Advisor. The initial term of the advisory agreement ends in July 2030, and will automatically renew for successive five-year terms unless either party gives written notice of its election not to renew at least 180 days prior to the then-applicable expiration date. We may only elect not to renew the advisory agreement on this basis with the prior approval of at least two-thirds of our independent directors, and no change of control fee (as defined in the advisory agreement) is payable if we make this election.

Asset Management Fees and Variable Management/Incentive Fees

We pay the Advisor a base asset management fee on the first business day of each month equal to (x) $0.5 million plus (y) a variable amount equal to (a) 1.25% of the equity proceeds received after November 16, 2018, divided by (b) 12. Equity proceeds are defined as, with respect to any period, cumulative net proceeds of all common and preferred equity and equity-linked securities issued by the Company and its subsidiaries during the period, including: (i) any equity issued in exchange or conversion of exchangeable notes based on the stock price at the date of issuance and convertible equity; (ii) any other issuances of equity, including but not limited to units in our New York City Operating Partnership L.P., our operating partnership (the "OP") (excluding equity-based compensation but including issuances related to an acquisition, investment, joint-venture or partnership); and (iii) any cumulative Core Earnings (as defined in the advisory agreement) in excess of cumulative distributions paid on our Common Stock since November 16, 2018, the effective date of the most recent amendment and restatement of the advisory agreement.

We also pay the Advisor an incentive variable management fee, payable quarterly in arrears based on the Company achieving certain amounts of Core Earnings Per Adjusted Share (as defined in the advisory agreement) on a quarterly basis. The quarterly thresholds of Core Earnings Per Adjusted Share are $1.17 and $1.56 per share, respectively. No incentive variable management fees were earned in the years ended December 31, 2025.

Both the base asset management fee and variable management fee are payable in cash, shares of Common Stock, units of limited partnership interest in the OP or a combination thereof, at the Advisor's election.

From February 1, 2023 through December 31, 2023, the Advisor was paid in cash for the base asset management fee. The Advisor was also paid cash for its management fee for January and February 2024. The Advisor elected to receive shares of Common Stock in lieu of cash in respect of its asset management fee for March, April and May 2024. As a result, in March 2024, the Company issued to the Advisor 70,607 shares of Common Stock for the monthly base asset management fee, 68,308 shares of Common Stock in April and 85,543 shares of Common Stock in May. The Advisor was paid cash for its management fee for the period of June 2024 through December 2025.

During the years ended December 31, 2025 and 2024, the Company paid base asset management fees in cash of $6.1 and $6.1 million, respectively. No variable management fees were paid during the years ended December 31, 2025 and 2024.

Amendment to Rights Agreement and Waiver Agreement

In connection with our rights offering which is expiring on August 18, 2025, our Board waived the limits contained in the Company's amended and restated rights agreement. In addition, our Board waived the

TABLE OF CONTENTS

existing limit imposed on purchases by Bellevue Capital and its affiliates including future issuances of Common Stock issued in lieu of the Company paying cash to the Advisor for asset management services. Bellevue Capital, the Advisor and other affiliates or person related to Bellevue Capital have granted an irrevocable proxy to the Company pursuant to which the Company has the right to vote any shares owned by these persons or entities in excess of 34.9% of the outstanding shares of Common Stock in the same proportion as all other shares voted by the Company's stockholders.

Side Letter With the Advisor

On February 4, 2022, the Company and the Advisor entered into a side letter (the "Side Letter") to the advisory agreement pursuant to which the Advisor agreed, from the date of the Side Letter until August 4, 2022, to immediately invest all fees received by the Advisor under Section 10(c)(i)-(ii) of the advisory agreement in shares of Common Stock (the "Shares"), in an amount aggregating no more than $3.0 million. The price of the Shares was determined, at each issuance, in accordance with Section 10(c)(iii) of the advisory agreement and was not less than the "Minimum Price" as defined in Section 312.04(h) of the New York Stock Exchange Listed Company Manual (the "Listed Company Manual"), which minimum price was $84.40 per share. The Advisor's obligation to invest its fee in Shares under the Side Letter was in consideration of, and subject to, the provisions of the Waiver Agreements (defined below). In addition, the Company was not required to issue any Shares under the Side Letter if doing so would have required the Company to seek stockholder approval under Section 312 of the Listed Company Manual or any subsequent rules and regulations of the NYSE.

On February 4, 2022, concurrently with the execution of the Side Letter, the Board granted (i) a waiver from the Aggregate Share Ownership Limit, as defined and contained in Section 5.7 of the Company's charter, to permit each of Bellevue Capital, the Advisor, entities controlled by Bellevue Capital, Edward M. Weil. Jr, who is a director of the Company, an officer of the Advisor and a holder of a non-controlling interest in Bellevue, and their respective affiliates and certain other entities and individuals who would be treated as Beneficially Owning or Constructively Owning (each as defined our charter) Shares held by either or both of Bellevue Capital and the Advisor, including Mr. Weil, to Beneficially Own or Constructively Own Shares in an amount up to 20% of the outstanding Shares (subject to certain constraints for each such entity and individual on the total actual ownership of Shares by such entities and individuals), to the extent and on the terms set forth in each ownership limit waiver agreement (collectively, the "Charter Ownership Limit Waiver Agreements"); and (ii) a waiver from the provisions contained in Section 1.1 of the Amended and Restated Rights Agreement, dated August 17, 2020 (as amended by Amendment No. 1 dated August 12, 2021, the "Rights Plan"), to permit each party to the Charter Ownership Limit Waiver Agreements to Beneficially Own (as defined in the Rights Plan) Shares to the maximum extent allowed by the Charter Ownership Limit Waiver Agreements without being deemed an "Acquiring Person" under Section 1.1 of the Rights Plan, subject to the terms set forth in the rights plan waiver agreement (the "Rights Plan Waiver Agreement," and together with the Charter Ownership Limit Waiver Agreements, the "Waiver Agreements").

On August 10, 2022, the Company (1) amended the Charter Ownership Limit Waiver Agreements to (i) immediately increase the Excepted Holder Limit (as defined therein) to 21%, and (ii) increase the Excepted Holder Limit to up to 25% upon conditions precedent being satisfied to increase the Excepted Holder Limit to up to 25% (the "Charter Waiver Agreement Amendments"), and (2) amended the Rights Plan Waiver Agreement to implement corresponding changes. Concurrent with these amendments, the Board reduced the Aggregate Share Ownership Limit to 6% for all stockholders of the Company other than Bellevue Capital, the Advisor, their respective affiliates or persons who would be treated as Beneficially Owning or Constructively Owning shares of Common Stock held by either or both of Bellevue Capital and the Advisor (the "Excluded Persons"). The terms and conditions of the Charter Ownership Limit Waiver Agreements entered into with each of these entities or individuals are the same except for the actual number of Shares the entities or individuals may own or acquire. All other terms and conditions contained in the Company's charter will otherwise continue to apply to the Shares that the entities or individuals may own or acquire.

As a consequence of the Company's decision to terminate our election to be taxed as a REIT, the ownership limitations set forth in Section 5.7 of the Company's charter, including, without limitation, the Aggregate Share Ownership Limit, no longer apply.

TABLE OF CONTENTS

Management Fee Expense

The Company recorded expense of $6.1 million for base asset management fees during the year ended December 31, 2025. No variable management fees were incurred.

Property Management Fees

Pursuant to the Property Management and Leasing Agreement (the "PMA"), as amended, except in certain cases where the Company contracted with a third party, the Company pays the Property Manager a property management fee equal to: (i) for non-hotel properties, 3.25% of gross revenues from the properties managed, plus market-based leasing commissions; and (ii) for hotel properties, a market-based fee based on a percentage of gross revenues. The term of the PMA is coterminous with the term of the advisory agreement.

Pursuant to the PMA, the Company reimburses the Property Manager for property-level expenses. These reimbursements are not limited in amount and may include reasonable salaries, bonuses, and benefits of individuals employed by the Property Manager, except for the salaries, bonuses, and benefits of individuals who also serve as one of the Company's executive officers or as an executive officer of the Property Manager or any of its affiliates. The Property Manager may also subcontract the performance of its property management and leasing services duties to third parties and pay all or a portion of its property management fee to the third parties with whom it contracts for these services.

On April 13, 2018, in connection with the loan for its 400 E. 67th Street - Laurel Condominium and 200 Riverside Boulevard properties the Company entered into a new property management agreement with the Property Manager (the "April 2018 PMA") to manage the properties secured by the loan. With respect to these properties, the substantive terms of the April 2018 PMA are identical to the terms of the PMA, except that the property management fee for non-hotel properties is 4.0% of gross revenues from the properties managed, plus market-based leasing commissions. The April 2018 PMA has an initial term of one year that is automatically extended for an unlimited number of successive one-year terms at the end of each year unless any party gives 60 days' written notice to the other parties of its intention to terminate.

The Company incurred approximately $1.2 million in property management fees during the year ended December 31, 2025.

On March 29, 2024, the Company, the OP and the Property Manager entered into the Third Amendment to the Property Management and Leasing Agreement (the "Third Amendment"). The Third Amendment provides that the Property Manager may elect to receive any fees payable in cash, OP Units, shares of the Company's common stock, or any combination thereof.

Professional Fees and Other Reimbursements

We are required to pay directly or reimburse the Advisor monthly in arrears, for all the expenses paid or incurred by the Advisor or its affiliates in connection with the services it provides to us under the advisory agreement, subject to the following limitations:

•

With respect to administrative and overhead expenses of the Advisor, including administrative and overhead expenses of all employees of the Advisor or its affiliates directly or indirectly involved in the performance of services but not including their salaries, wages, and benefits, these costs may not exceed in any fiscal year,

(i)

$0.4 million, or

(ii)

if the Asset Cost (as defined in the advisory agreement) as of the last day of the fiscal quarter immediately preceding the month is equal to or greater than $1.25 billion, (x) the Asset Cost as of the last day of the fiscal quarter multiplied by (y) 0.10%.

•

With respect to the salaries, wages, and benefits of all employees of the Advisor or its affiliates directly or indirectly involved in the performance of services (which may include the Company's executive officers), these amounts must be comparable to market rates and reimbursements may not exceed, in any fiscal year,

(i)

$2,971,969, or

TABLE OF CONTENTS

(ii)

if the Asset Cost as of the last day of the fiscal year is equal to or greater than $1.25 billion, (x) the Asset Cost as of the last day of the fiscal year multiplied by (y) 0.30%.

On March 29, 2024, we, the OP and the Advisor entered into the Second Amendment to the Second Amended and Restated Advisory Agreement (the "Second Amendment"). The Second Amendment increased the limit on the salaries, wages, and benefits of all employees of the Advisor or its affiliates directly or indirectly involved in the performance of services (including our executive officers) to the lesser of (i) $2,971,969 or (ii) if the Asset Cost as of the last day of such fiscal year is equal to or greater than $1.25 billion, (x) the Asset Cost as of the last day of such fiscal year multiplied by (y) 0.30%. The Second Amendment further provides that Advisor Employee Compensation Limit will be further increased by an annual cost of living adjustment equal to the Advisor Employee Compensation Limit (as determined above) multiplied by the greater of (x) 3.0% and (y) the Consumer Price Index for the prior year ended December 31st. The Second Amendment also provides that our Advisor may elect to receive any expense reimbursement amounts in cash, OP Units, shares of the Company's common stock, or any combination thereof.

Professional fees and other reimbursements for the year ended December 31, 2025 were $4.9 million. These amounts include reimbursements to the Advisor for administrative, overhead and personnel services, which are subject to the limits noted above, as well as costs associated with directors and officers insurance which are not subject to those limits.

The amount of expenses included within professional fees and other reimbursements related to administrative, overhead and personnel services provided by and reimbursed to the Advisor for the year ended December 31, 2025 were $3.4 million, of which $0.4 million related to administrative and overhead expenses and $3.0 million were for salaries, wages, and benefits.

The following table details amounts incurred, waived and payable in connection with the Company's operations-related services described above as of and for the periods presented:

	Year Ended December 31, 2025			Payable (Receivable) Incurred December 31, 2025
(In thousands)	Incurred			Payable (Receivable) Incurred December 31, 2025
Ongoing fees:
Asset and property management fees to related parties		$	7,281		-
Professional fees and other reimbursements(2)			4,122		-
Total related party operation fees and reimbursements		$	11,403		-

(2)

Amount for the year ended December 31, 2025 is included in general administrative expenses in the consolidated statements of operations and comprehensive loss.

Termination Payments

The advisory agreement requires the Company to pay a termination fee to the Advisor if the advisory agreement is terminated prior to the expiration of the initial term in certain limited scenarios. The termination fee will be payable to the Advisor if either the Company or the Advisor exercises the right to terminate the advisory agreement in connection with the consummation of the first "change of control" (as defined in the advisory agreement). The termination fee is equal to $15.0 million plus an amount equal to the product of: (i) four multiplied by (ii) applicable Subject Fees (as defined in the advisory agreement). The "Subject Fees" are equal to: (i) the product of (a) 12, multiplied by (b) the actual base management fee for the month immediately prior to the month in which the advisory agreement is terminated, plus (ii) the product of (x) four multiplied by (y) the actual variable management fee for the quarter immediately prior to the quarter in which the advisory agreement is terminated, plus (iii) without duplication, the annual increase in the base management fee resulting from the cumulative net proceeds of any equity issued by the Company and its subsidiaries in respect of the fiscal quarter immediately prior to the fiscal quarter in which the advisory agreement is terminated.

In connection with the termination or expiration of the advisory agreement, the Advisor will be entitled to receive (in addition to any termination fee) all amounts then accrued and owing to the Advisor, including an amount equal to then-present fair market value of its shares of Common Stock and interest in the OP.

TABLE OF CONTENTS

Indemnification Obligations

Subject to conditions and exceptions, the Company has agreed to indemnify the Advisor and its affiliates, including their respective officers, directors, partners and employees, from and against all losses, claims, damages, or losses and related expenses (including reasonable attorneys' fees) arising in the performance of their duties under the advisory agreement.

We have entered into indemnification agreements with the Advisor and certain of its affiliates, each of our directors and officers, and certain former directors and officers, providing that we will indemnify them to the extent permitted by Maryland law and advance expenses to them in connection with claims or liability they may become subject to due to their service to us consistent with the provisions of Maryland law.

There have been no complaints, the Advisor has not made any requests and we have not paid the Advisor or any of its affiliates for any amounts pursuant to these obligations through the date of this Proxy Statement.

Certain Conflict Resolution Procedures

Every transaction that we enter into with the Advisor or its affiliates is subject to an inherent conflict of interest. Our Board of Directors may encounter conflicts of interest in enforcing our rights against any of these entities in the event of a default by or disagreement with or in invoking powers, rights or options pursuant to any agreement between us and the Advisor or any of its affiliates.

The nominating and corporate governance committee is responsible for reviewing and evaluating all related party transactions. All related party transactions during the years ended December 31, 2025 and 2024 and during the period from January 1, 2026 through the date of this Proxy Statement were approved in accordance with the applicable Company policies consistent with the nominating and corporate governance committee charter, as applicable. Either our nominating and corporate governance committee or the independent directors acting as a group or as a special committee, has determined that each related party transaction was in the best interests of the Company. See "Board of Directors, Executive Officers and Corporate Governance - Nominating and Corporate Governance Committee."

In addition, the advisory agreement limits our ability to enter into transactions with the Advisor and its affiliates as follows:

•

If we propose to enter into any transaction in which the Advisor, any affiliate of the Advisor or any of the Advisor's directors or officers has a direct or indirect interest, then the transaction must be approved by a majority of our directors not otherwise interested in the transaction, including a majority of our independent directors.

•

We may not make loans to the Advisor or any of its affiliates except mortgages or loans to wholly owned subsidiaries of ours. The Advisor and its affiliates may not make loans to us, or to any joint venture or partnership or other similar arrangements in which we are a co-venturer, limited liability company member, limited partner or general partner, which are established to acquire or hold our investments, unless approved by a majority of our directors (including a majority of our independent directors) not otherwise interested in the transaction as fair, competitive, and commercially reasonable, and no less favorable to us than comparable loans between unaffiliated parties.

•

We may enter into joint ventures or other similar arrangements with the Advisor or its affiliates provided that (a) a majority of our directors (including a majority of our independent directors) not otherwise interested in the transaction approves the transaction as being fair and reasonable to us, and (b) the investment by us is on substantially the same terms as those received by other joint venturers.

TABLE OF CONTENTS

AUDIT COMMITTEE REPORT

The Audit Committee of the Board has furnished the following report on its activities during the year ended December 31, 2025. The report is not deemed to be "soliciting material" or "filed" with the SEC or subject to the SEC's proxy rules or to the liabilities of Section 18 of the Exchange Act, and the report shall not be deemed to be incorporated by reference into any prior or subsequent filing under the Securities Act of 1933, as amended (the "Securities Act"), or the Exchange Act except to the extent that the Company specifically incorporates it by reference into any such filing.

To the Directors of American Strategic Investment Co.:

We have reviewed and discussed with management American Strategic Investment Co.'s audited financial statements as of and for the year ended December 31, 2025.

We have discussed with the independent registered public accounting firm the matters required to be discussed by the applicable requirements of the Public Company Accounting Oversight Board and the Securities and Exchange Commission.

We have received the written disclosures and the letter from the independent registered public accounting firm required by applicable requirements of the Public Company Accounting Oversight Board regarding the independent registered public accounting firm's communications with the audit committee concerning independence, and have discussed with the independent registered public accounting firm the independent registered public accounting firm's independence.

Based on the reviews and discussions referred to above, we recommended to the Board of Directors that the financial statements referred to above be included in American Strategic Investment Co.'s Annual Report to Stockholders for the year ended December 31, 2025.

Audit Committee

Louis P. DiPalma (Chair)
Elizabeth K. Tuppeny
Nicholas Radesca

TABLE OF CONTENTS

COMPENSATION COMMITTEE REPORT

The Compensation Committee of the Board has furnished the following report during the year ended December 31, 2025. The report is not deemed to be "soliciting material" or "filed" with the SEC or subject to the SEC's proxy rules or to the liabilities of Section 18 of the Exchange Act, and the report shall not be deemed to be incorporated by reference into any prior or subsequent filing under the Securities Act, or the Exchange Act except to the extent that the Company specifically incorporates it by reference into any such filing.

To the Directors of American Strategic Investment Co.:

We have reviewed and discussed the "Compensation Discussion and Analysis" required by Item 402(b) of Regulation S-K of the Securities Exchange Act of 1934, as amended, with management.

Based on the review and discussions described above, we recommended to the Board of Directors of American Strategic Investment Co. that the "Compensation Discussion and Analysis" be included in the American Strategic Investment Co.'s proxy statement.

Compensation Committee

Elizabeth K. Tuppeny
Nicholas Radesca

TABLE OF CONTENTS

PROPOSAL NO. 1 - ELECTION OF DIRECTORS

Our Board of Directors is currently comprised of four members, three of whom are independent directors. Our Bylaws provide that the number of directors may not be less than one, which is the minimum number required by the MGCL, or more than 15. The Board of Directors is divided into three classes of directors. Each director serves until the annual meeting of stockholders held in the third year following the year of his or her election and until his or her successor is duly elected and qualifies. At the Annual Meeting, two Class III directors will be elected to serve until the 2029 Annual Meeting and until their respective successors are duly elected and qualify. The number of directors in each class may be changed from time to time by the Board to reflect matters such as an increase or decrease in the number of directors so that each class, to the extent possible, will have the same number of directors.

The Board of Directors has nominated Louis P. DiPalma and Edward M. Weil, Jr. for election as a Class III directors to serve until our 2029 Annual Meeting and until their respective successors are duly elected and qualify. Each of Messrs. DiPalma and Weil currently serve as Class III directors of the Company and agreed to be named in this Proxy Statement and to serve as a director if elected.

The proxy holders named on the proxy card intend to vote "FOR" the election of each of Messrs. DiPalma and Weil as a Class III director. The election of the Class III directors require the affirmative vote of a plurality of all the votes cast at the Annual Meeting, provided that a quorum is present. Withhold votes and broker non-votes, if any, will have no effect on the result of the vote, although they will be considered present for the purpose of determining the presence of a quorum.

We know of no reason why Messrs. DiPalma or Weil will be unable to serve if elected. If, at the time of the Annual Meeting, Messrs. DiPalma or Weil should become unable to serve, shares represented by the proxies will be voted "FOR" any substitute nominee designated by the Board of Directors. No proxy will be voted for a greater number of persons than the number of nominees described in this Proxy Statement.

THE BOARD OF DIRECTORS RECOMMENDS THAT THE STOCKHOLDERS VOTE "FOR" THE ELECTION OF EACH OF LOUIS P. DIPALMA AND EDWARD M. WEIL, JR. AS A CLASS III DIRECTOR, TO SERVE UNTIL THE COMPANY'S 2029 ANNUAL MEETING AND UNTIL THEIR SUCCESSORS ARE DULY ELECTED AND QUALIFY.

TABLE OF CONTENTS

PROPOSAL NO. 2 - RATIFICATION OF APPOINTMENT OF INDEPENDENT
REGISTERED PUBLIC ACCOUNTING FIRM

The audit committee of the Board of Directors has selected and appointed CBIZ as our independent registered public accounting firm to audit our consolidated financial statements for the year ending December 31, 2026.

Although ratification by stockholders is not required by law, our charter or Bylaws, our audit committee believes that submission of its selection to stockholders is a matter of good corporate governance. CBIZ reports directly to our audit committee. Even if the appointment is ratified, our audit committee, in its discretion, may select a different independent registered public accounting firm at any time if our audit committee believes that such a change would be in the best interests of the Company. If our stockholders do not ratify the appointment of CBIZ, our audit committee will take that fact into consideration, together with such other factors it deems relevant, in determining its next selection of an independent registered public accounting firm.

This proposal requires the affirmative vote of a majority of all of the votes cast at the Annual Meeting, provided that a quorum is present. Abstentions will not be counted as votes cast and will have no effect on the result of the vote on this proposal, although they will be considered present for the purpose of determining the presence of a quorum. Because brokers have discretionary voting authority with regard to this proposal we do not expect any broker non-votes in connection with this proposal.

A representative of CBIZ will attend the Annual Meeting and will have an opportunity to make a statement if he or she desires to do so and will be available to respond to appropriate questions.

Fees

CBIZ was our independent registered public accounting firm for the fiscal year ended December 31, 2025. PricewaterhouseCoopers LLP ("PwC") was our independent registered public accounting firm for the fiscal year ended December 31, 2024.

The following table summarizes the fees billed to us for professional services rendered by PwC & CBIZ, all of which have been approved by the audit committee, for the fiscal years ended December 31, 2025 and 2024, respectively:

CBIZ

	2025			2024
Audit Fees		$	171,200		-
Audit Related fees			-		-
Tax Fees			-		-
All Other Fees			-		-
Total		$	171,200		-

PwC

	2025			2024
Audit Fees		$	617,500		$	1,328,873
Audit Related fees			-			-
Tax Fees			-			-
All Other Fees			-			-
Total		$	617,500		$	1,328,873

Pre-Approval Policies and Procedures

In considering the nature of the services provided by the independent registered public accounting firm, our audit committee determined that the services are compatible with the provision of independent audit

TABLE OF CONTENTS

services. Our audit committee discussed these services with the independent registered public accounting firm and the Company's management to determine that they are permitted under the rules and regulations concerning auditor independence promulgated by the SEC to implement the related requirements of the Sarbanes-Oxley Act of 2002, as well as the American Institute of Certified Public Accountants. All services rendered by CBIZ and PwC were pre-approved by the audit committee.

THE BOARD OF DIRECTORS RECOMMENDS THAT THE STOCKHOLDERS VOTE "FOR" THE RATIFICATION OF THE APPOINTMENT OF PRICEWATERHOUSECOOPERS LLP AS THE COMPANY'S INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM FOR THE YEAR ENDING DECEMBER 31, 2026.

Change in Certifying Accountant

On October 16, 2025, our audit committee dismissed PwC as our independent registered public accounting firm, effective immediately. The decision to change our independent registered public accounting firm was the result of a competitive bid process, as well as a focus on streamlining our cost structure and reducing general and administrative expenses.

PwC performed audits of our consolidated financial statements for the years ended December 31, 2023 and 2024. PwC's reports for such years did not contain an adverse opinion or a disclaimer of opinion and were not qualified or modified as to uncertainty, audit scope, or accounting principles, except for an emphasis of matter paragraph regarding the Company's significant liquidity constraints contained in its audit report for the fiscal year ended December 31, 2024.

During the two years ended December 31, 2024, and the subsequent interim period through October 16, 2025, there were no (i) disagreements (as defined in Item 304(a)(1)(iv) of Regulation S-K and the related instructions to Item 304 of Regulation S-K promulgated by the SEC pursuant to the Securities Exchange Act of 1934, as amended) between the Company and PwC on any matter of accounting principles or practices, financial statement disclosure, or auditing scope or procedure, which disagreements, if not resolved to satisfaction of PwC, would have caused PwC to make reference to the subject matter of such disagreements in connection with its report, or (ii) "reportable events," as described in Item 304(a)(1)(v) of Regulation S-K, that would require disclosure under Item 304(a)(1)(v) of Regulation S-K.

Our Audit Committee invited several public accounting firms to participate in bid process, and as a result of this process, on October 16, 2025, the Audit Committee appointed CBIZ to serve as our independent registered public accounting firm for the fiscal year ending December 31, 2025, including the review of the interim unaudited financial statements and related notes to be included in our Quarterly Report on Form 10-Q for the fiscal quarter ended September 30, 2025, subject to CBIZ's completion of its customary client acceptance procedures and execution of an engagement letter.

During the two years ended December 31, 2024, and the subsequent interim period through the appointment of CBIZ as our independent registered public accounting firm on October 16, 2025, neither we nor anyone acting on our behalf consulted CBIZ CPAs regarding either: (i) the application of accounting principles to a specified transaction, either completed or proposed; or the type of audit opinion that might be rendered on the Company's financial statements, and no written report or oral advice was provided to the Company by CBIZ that CBIZ concluded was an important factor considered by the Company in reaching a decision as to an accounting, auditing or financial reporting issue; or (ii) any matter that was either subject of a disagreement, as that term is defined in Item 304 (a)(1)(iv) of Regulation S-K and the related instructions to Item 304 of Regulation S-K, or a "reportable event," as that term is described in Item 304(a)(1)(v) of Regulation S-K.

We furnished PwC with a copy of the disclosure contained under this heading "Changes in Certifying Accountant" prior to filing a Current Report on Form 8-K containing such disclosure with the SEC on October 21, 2025 and requested that PwC furnish us with a letter addressed to the SEC stating whether or not it agreed with the statements reported pursuant to Item 304(a) of Regulation S-K in such Current Report on Form 8-K. A copy of PwC's letter addressed to the SEC dated October 21, 2025 was attached as Exhibit 16.1 to the Current Report on Form 8-K filed by us on October 21, 2025.

TABLE OF CONTENTS

PROPOSAL NO. 3 - NON-BINDING ADVISORY VOTE ON EXECUTIVE COMPENSATION

Pursuant to Section 14A of the Exchange Act, we are providing our stockholders with the opportunity to vote on a non-binding, advisory resolution regarding executive compensation, as disclosed in this Proxy Statement. This proposal, known as a "say-on-pay" proposal, gives our stockholders the opportunity to express their views on this matter. Approval of this non-binding advisory resolution requires the affirmative vote of a majority of the votes cast with respect to this proposal.

We have no employees. The Advisor performs our day-to-day management functions and affiliates of the Advisor employ the persons who provide these services, including our named executive officers. Pursuant to the terms of the advisory agreement, we pay the Advisor management fees and reimburse the Advisor for certain expenses as required by the terms of our advisory agreement. For further details regarding the advisory agreement and our other arrangements with the Advisor and its affiliates, including the Property Manager, see "Certain Relationships and Related Transactions." Please note, stockholders are not being asked to vote on the terms of the advisory agreement.

As an externally managed company, we do not employ our named executive officers, have agreements with them regarding their compensation or otherwise determine the compensation earned by, or paid to, them. AR Global, the parent company of the Advisor, determines the salaries, bonuses and other benefits earned by or paid to our named executive officers. We are required by the terms of our advisory agreement to reimburse the Advisor for salaries, bonuses or benefits of certain of our named executive officers, subject to certain limits described in more detail herein. We are not involved in establishing the compensation for the employees of the Advisor and its affiliates and do not have approval rights regarding the amounts paid to those persons. We limit the amount of aggregate reimbursement as described herein and reflected in the advisory agreement.

In accordance with Section 14A of the Exchange Act, we are asking stockholders to approve, on a non-binding, advisory basis, the following resolution at the annual meeting:

"RESOLVED, that the compensation of the Company's named executive officers, as disclosed in this Proxy Statement pursuant to the compensation disclosure rules of the SEC, including the compensation tables and related narrative discussion, is hereby approved."

This resolution is advisory and non-binding. Our obligation to reimburse the Advisor for amounts incurred by the Advisor for salaries, bonuses or benefits of certain of our named executive officers is governed by the terms of the advisory agreement with the Advisor, which does not expire until July 2030, and cannot be amended except with the mutual consent of the parties.

THE BOARD OF DIRECTORS RECOMMENDS THAT THE STOCKHOLDERS VOTE "FOR" THE ADOPTION OF THIS NON-BINDING ADVISORY RESOLUTION.

TABLE OF CONTENTS

CODE OF ETHICS AND CORPORATE GOVERNANCE GUIDELINES

Code of Business Conduct and Ethics

The Board adopted an Amended and Restated Code of Business Conduct and Ethics (the "Code of Ethics") that applies to all of our executive officers and directors, including but not limited to, our principal executive officer and principal financial officer. We have also adopted corporate governance guidelines to assist the Board of Directors in the exercise of its responsibilities.

A copy of our Code of Ethics and corporate governance guidelines may be obtained, free of charge, by sending a written request to our executive office: 222 Bellevue Ave., Newport, Rhode Island 02840, Attention: Chief Financial Officer. Our Code of Ethics and corporate governance guidelines are also publicly available on our website at www.americanstrategicinvestment.com. If we make any substantive amendments to the Code of Ethics or grant any waiver, including any implicit waiver, from a provision of the Code of Ethics, we will disclose the nature of the amendment or waiver on that website or in a current report on Form 8-K.

Insider Trading Policy

We have adopted an insider trading policy (the "Insider Trading Policy") which governs the purchase, sale and/or any other dispositions of the Company's securities by the Company and its directors, officers and employees and is reasonably designed to promote compliance with insider trading laws, rules and regulations and applicable exchange listing standards. A copy of the Insider Trading Policy has been filed with our 2025 10-K.

OTHER MATTERS PRESENTED FOR ACTION AT THE ANNUAL MEETING

Except as described herein, our Board does not intend to present for consideration at the Annual Meeting thereof any matter other than those specifically set forth in the Notice of Annual Meeting of Stockholders. If any other matter is properly presented for consideration at the meeting, either of the persons named in the proxy, acting individually and without the other, will vote thereon pursuant to his or her discretion, to the extent permitted by Rule 14a-4(c) under the Exchange Act.

TABLE OF CONTENTS

STOCKHOLDER PROPOSALS FOR THE 2027 ANNUAL MEETING

Stockholder Proposals in the Proxy Statement

Rule 14a-8 under the Exchange Act addresses when a company must include a stockholder's proposal in its proxy statement and identify the proposal in its form of proxy when the Company holds an annual or special meeting of stockholders. Stockholder proposals submitted under Rule 14a-8 must be submitted in accordance with the procedures specified in the rule and be received at our principal executive offices by December 18, 2026. Any proposal received after such date will be considered untimely.

Stockholder Proposals and Nominations for Directors to Be Presented at Meetings

Requests for inclusion of any nominations of an individual to serve as a director or other business proposal under our Bylaws must be submitted in accordance with the procedures set forth in our Bylaws and include the information specified in the Bylaws. Under our current Bylaws, nominations of individuals to serve as directors or other business proposals must be in writing and, to be properly submitted for presentation at our 2026 Annual Meeting, must be delivered to our secretary at our principal executive offices during the period beginning on November 24, 2026 and ending at 5:00 p.m., Eastern Time, on December 24, 2026. In addition, in order to comply with the SEC's universal proxy rules, any stockholder who intends to solicit proxies in support of director nominees other than our nominees for the 2027 Annual Meeting must also provide notice that sets forth the information required by Rule 14a-19(b) under the Exchange Act no later than April 3, 2027, including providing a statement that such stockholder intends to solicit the holders of shares of Common Stock representing at least 67% of the voting power of the Common Stock entitled to vote on the election of directors in support of director nominees other than the Company's nominees; however, Rule 14a-19's notice requirement does not override or supersede the longer notice period established by our Bylaws, and the longer time period contained in our Bylaws controls. If the 2027 Annual Meeting is changed by more than 30 calendar days from the first anniversary of the 2026 Annual Meeting, stockholders must also provide notice that sets forth the information required by Rule 14a-19(b) under the Exchange Act no later than the later of 60 calendar days prior to the date of the 2027 Annual Meeting or the 10th calendar day following the day on which public announcement of the date of the 2027 Annual Meeting is first made. If a stockholder notifies us of an intent to present a proposal at the 2027 Annual Meeting at any time after March 9, 2027 (and for any reason the proposal is voted on at that meeting), it will be considered untimely and our proxy holders will have the right to exercise discretionary voting authority with respect to the proposal, if presented at the meeting, without including information regarding the proposal in our proxy materials.

All nominations and other business proposals should be sent via registered, certified or express mail to our secretary at our principal executive offices at: American Strategic Investment Co., 222 Bellevue Ave., Newport, Rhode Island 02840, Attention: Secretary (telephone: (212) 415-6500).

				By Order of the Board of Directors,
				/s/ Nicholas S. Schorsch, Jr.
				Nicholas S. Schorsch, Jr. Chief Executive Officer

TABLE OF CONTENTS

01 - Edward M. Weil2 2 B VFor Withhold02 - Louis P. DiPalmaFor WithholdProposals - THE BOARD OF DIRECTORS UNANIMOUSLY RECOMMENDED A THAT YOU VOTE "FOR" EACH OF THE PROPOSALS.04A2HC2. The ratification of the appointment of CBIZ CPAs P.C. (CBIZ) asthe Company's independent registered public accounting firmfor the year ending December 31, 2026.3. The adoption of a non-binding advisory resolution regardingexecutive compensation.4. The transaction of such other matters as may properly comebefore the Annual Meeting.1. The election of two Class III directors to serve until our 2029 Annual Meeting of stockholders and until their successor is duly elected and qualifies:For Against Abstain For Against AbstainPlease sign exactly as name(s) appears hereon. Joint owners should each sign. When signing as attorney, executor, administrator, corporate officer, trustee, guardian, or custodian, please give full title.Date (mm/dd/yyyy) - Please print date below. Signature 1 - Please keep signature within the box. Signature 2 - Please keep signature within the box.B Authorized Signatures - This section must be completed for your vote to count. Please date and sign below.2026 Annual Stockholders Meeting Proxy CardUsing a black ink pen, mark your votes with an X as shown in this example.Please do not write outside the designated areas.q IF VOTING BY MAIL, SIGN, DETACH AND RETURN THE BOTTOM PORTION IN THE ENCLOSED ENVELOPE.qYou may vote online or by phone instead of mailing this card.OnlineGo to www.envisionreports.com/NYCor scan the QR code - login details arelocated in the shaded bar below.Your vote matters - here's how to vote!Save paper, time and money!Sign up for electronic delivery atwww.envisionreports.com/NYCPhoneCall toll free 1-800-652-VOTE (8683) withinthe USA, US territories and Canada

TABLE OF CONTENTS

Small steps make an impact.Help the environment by consenting to receive electronicdelivery, sign up at www.envisionreports.com/NYCNotice of 2026 Annual Meeting of StockholdersTHIS PROXY IS BEING SOLICITED BY THE BOARD OF DIRECTORSThe undersigned stockholder(s) of American Strategic Investment Co., a Maryland corporation (the "Company"), revoking previous proxies, hereby appointsNicholas S. Schorsch, Jr. and Michael LeSanto, or any one of them, true and lawful attorneys with power of substitution of each, to vote all shares of AmericanStrategic Investment Co., which the undersigned is entitled to vote, at the 2026 Annual Meeting of Stockholders ("Annual Meeting") to be held virtually only,on Tuesday, June 2, 2026, commencing at 2:00 p.m. Eastern Time, at the following Website: meetnow.global/MLJAF4H. To participate in the Virtual Meetingplease follow the instructions in the Proxy Materials and enter the 15-digit control number from the shaded box on this card.The undersigned hereby revokes any and all previous proxies with respect to such shares heretofore by the undersigned.Receipt of the Notice of Annual Meeting and the accompanying Proxy Statement is hereby acknowledged by the undersigned. If this Proxy is executed but noinstructions are given, the votes entitled to be cast by the undersigned will be cast "FOR" each of the Proposals. Additionally, in their discretion, the proxyholders named above are authorized to vote upon such other matters as may properly come before the Annual Meeting or any adjournment or postponementthereof.(Items to be voted appear on reverse side)Proxy - AMERICAN STRATEGIC INVESTMENT CO.C Non-Voting Itemsq IF VOTING BY MAIL, SIGN, DETACH AND RETURN THE BOTTOM PORTION IN THE ENCLOSED ENVELOPE.qChange of Address - Please print new address below. Comments - Please print your comments below.Important notice regarding the Internet availability of proxy materials for the 2026 Annual Meeting of Stockholders.The 2026 Proxy Statement and 2025 Annual Report on Form 10-K for this meeting are available at:www.envisionreports.com/NYCIF YOU VOTE ON THE INTERNET OR BY TELEPHONE,YOU NEED NOT RETURN THIS PROXY CARDThe 2026 Annual Meeting of Stockholders of American Strategic Investment Co. will be held onTuesday, June 2, 2026 at 2:00 p.m. Eastern Time, virtually via the internet at meetnow.global/MLJAF4H.To access the virtual meeting, you must have the information that is printed in the shaded barlocated on the reverse side of this form.

American Strategic Investment Co. published this content on April 23, 2026, and is solely responsible for the information contained herein. Distributed via EDGAR on April 23, 2026 at 20:39 UTC. If you believe the information included in the content is inaccurate or outdated and requires editing or removal, please contact us at [email protected]