Arcturus Therapeutics Holdings Inc.

09/26/2025 | Press release | Distributed by Public on 09/26/2025 04:06

Meiji Seika Pharma Launches Two-Dose Vial of KOSTAIVE®, a Self-Amplifying mRNA COVID-19 Vaccine, in Japan (Form 8-K)

Meiji Seika Pharma Launches Two-Dose Vial of KOSTAIVE®, a Self-Amplifying mRNA COVID-19 Vaccine, in Japan

Meiji Seika Pharma Co., Ltd. (Headquarter: Tokyo, Japan; President and Representative Director: Toshiaki Nagasato) announced today that it launched a new presentation of KOSTAIVE®, a self-amplifying mRNA vaccine against COVID-19, supplied in vials, each containing two doses.

The product targets the SARS-CoV-2 Omicron sublineage JN.1 variant XEC. In non-clinical studies, it induced neutralizing antibodies not only against Omicron JN.1 and XEC, but also against LP.8.1 and the currently circulating variants XFG and NB.1.8.1. The formulation is supplied as a two-dose vial, with one vial per carton.

Meiji Seika Pharma remains committed to contributing to the prevention of COVID-19.

About sa-mRNA

mRNA vaccines help protect against infectious diseases by providing a blueprint for cells in the body to make a protein to help our immune systems recognize and fight the disease. Compared to standard mRNA vaccines, self-amplifying mRNA vaccines instruct the body to make more mRNA and spike protein to generate a more durable immune response

Brand Name KOSTAIVE intramuscular injection
Antigen strain SARS-CoV-2 Omicron sublineage JN.1 variant XEC
Active ingredient Coronavirus (SARS-CoV-2) self-amplifying mRNA vaccine
Use & Dosage

Dissolve this drug in 1.5 mL of Japanese Pharmacopoeia physiological saline solution.

Administer a single dose of 0.5 mL intramuscularly

Date of Manufacturing and Marketing Approval August 28, 2025
Date of Launch in Japan September 26, 2025
Packaging 1 vial

*For further information, please refer to the package insert.

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