Material Event (Form 8-K)

Item 8.01 Other Events.

On August 24, 2026, Erasca, Inc. (the "Company") announced that the U.S. Food and Drug Administration ("FDA") has granted Fast Track Designation ("FTD") to ERAS-0015 for the treatment of patients with metastatic pancreatic adenocarcinoma.

FTD is intended to facilitate development and expedite the review of therapies for serious conditions with unmet medical needs. Designated programs may benefit from more frequent interactions with the FDA and, if relevant criteria are met, may be eligible for benefits such as accelerated approval, priority review, and rolling review. FTD does not change the standards for approval but may expedite the development or approval process. Even if a product qualifies for FTD, the FDA may later decide that the product no longer meets the conditions for qualification or decide that the time period for FDA review or approval will not be shortened.