Prospectus Certification by Investment Company (Form 497J)

[Janus Henderson Letterhead]

March 9, 2026

EDGAR Operations Branch

Securities and Exchange Commission

Division of Investment Management

100 F Street, N.E.

Washington, D.C. 20549-0505

1933 Act File No. 002-34393

1940 Act File No. 811-01879

Dear Sir or Madam:

Pursuant to Rule 497(j) of Regulation C under the Securities Act of 1933, as amended (the "1933 Act"), the undersigned hereby certifies on behalf of the Registrant:

1. There are no changes to the Prospectuses and Statement of Additional Information ("SAI") from the forms of the Prospectuses and SAI that were filed in Post-Effective Amendment No. 335 ("PEA No. 335") on March 4, 2026, pursuant to Rule 485(b) under the 1933 Act for Janus Hendersom Low Duration Multi-Sector Income Fund (formally named Janus Henderson Absolute Return Income Opportunities Fund), and all share classes thereof.

2. The text of PEA No. 335 has been filed electronically.

If you have any questions regarding this filing, please call me at (303) 336-7889 or email me at [email protected].

Respectfully,

/s/ Jay Mensah

Jay Mensah

Assistant Secretary

Enclosure (via EDGAR)

Thea Kelley