Failure to Satisfy Listing Rule (Form 8-K)

On September 14, 2025, the Nasdaq Stock Market ("Nasdaq") notified ZyVersa Therapeutics, Inc. (the "Company") that, on September 18, 2025, it will announce the delisting of the Company's common stock. The Company's common stock was suspended from trading on The Nasdaq Capital Market on July 17, 2025, and has been trading on the OTCQB® Venture Market (the "OTCQB") under the symbol "ZVSA" since July 28, 2025. Nasdaq will file a Form 25 with the Securities and Exchange Commission (the "SEC") to complete the delisting in accordance with Rule 12d2-2 promulgated under the Securities Exchange Act of 1934, as amended. The delisting will become effective ten days after the Form 25 is filed. The Company's common stock will continue trading on the OTCQB without disruption.

As previously reported on the Company's Current Report on Form 8-K filed with the SEC on July 16, 2025, the Company received written notice from the Nasdaq Hearings Panel (the "Panel") on July 15, 2025, indicating that the Panel had determined to delist the Company's securities from Nasdaq and that trading in the Company's securities would be suspended at the open of trading on July 17, 2025, due to the Company's failure to regain compliance with the minimum bid price requirements under Listing Rule 5550(a)(2).

CAUTIONARY NOTE REGARDING FORWARD-LOOKING STATEMENTS

This Current Report on Form 8-K ("Form 8-K") contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. All statements contained in this Form 8-K that do not relate to matters of historical fact should be considered forward-looking statements, including, but not limited to, statements regarding the timing of the delisting of the Company's common stock. Actual results and the timing of events could differ materially from those anticipated in such forward-looking statements as a result of risks, uncertainties and other important factors, including those factors discussed under the caption "Risk Factors" in the Company's Annual Report on Form 10-K for the year ended December 31, 2024, as updated by the Company's Quarterly Report on Form 10-Q for the quarter ended June 30, 2024, in each case as filed with the SEC, could cause actual results to differ materially from those indicated by the forward-looking statements made in this Form 8-K. Any forward-looking statements speak only as of the date of this Form 8-K and are based on information available to the Company as of the date of this Form 8-K, and the Company assumes no obligation to, and does not intend to, update any forward-looking statements, whether as a result of new information, future events or otherwise.