Regulation FD Disclosure (Form 8-K)

Item 7.01 Regulation FD Disclosure.

On August 26, 2025, Lineage Cell Therapeutics, Inc. ("we," "us," "our," the "Company," or "Lineage") issued a press release announcing that it entered into a multi-year research collaboration agreement with William Demant Invest 2 Aps ("WDI") to advance the preclinical development of Lineage's auditory neuronal cell transplant program, ReSonanceTM(ANPI), for the treatment of hearing loss. A copy of the press release is furnished as Exhibit 99.1 hereto.

The information in this Item 7.01 and in Exhibit 99.1 to this report is being furnished and is not being filed for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), and is not to be incorporated by reference into any filing of the registrant under the Securities Act of 1933, as amended, or the Exchange Act, whether made before or after the date hereof, regardless of any general incorporation language in any such filing, except as shall be expressly set forth by specific reference in such a filing.

Item 8.01 Other Events.

On August 22, 2025, Lineage and WDI entered into a research collaboration agreement (the "RCA") to advance the preclinical development of Lineage's auditory neuronal cell transplant program, ReSonance (ANPI), for the treatment of hearing loss (the "Project"). WDI will fund up to $12 million in research collaboration costs over the approximate three-year term of the RCA. The main objective of the RCA is for the parties to complete a preclinical phase achieving readiness to potentially progress to human clinical trials under one or more separate clinical agreements, the terms of which would be negotiated in good faith before the expiration of the RCA.

All intellectual property owned by a party prior to the date of the RCA will remain their sole and exclusive property. The parties will jointly own all results, data, reports, know-how and patent(s) conceived or otherwise generated in the course of and resulting from the Project (the "Project Results"), other than discoveries or developments relating to Lineage's prioprietary platform technology.

If a party (the "abandoning party") informs the other party (the "continuing party") that it will not continue the research with the other party under a clinical agreement, the continuing party may purchase the abandoning party's ownership interest in the intellectual property resulting from the Project for exploitation for the treatment of hearing loss and a license to the abandoning party's background intellectual property to the extent necessary for such exploitation for an amount and on terms to be determined by the mutual agreement of the parties, and if such mutual agreement is not reached, by an independent third-party.

Item 9.01 Financial Statements and Exhibits.

(d) Exhibits.