Corporate Action, Termination of Material Agreement (Form 8-K)

On September 24, 2025, Unity Biotechnology, Inc. (the "Company") entered into a Lease Termination Agreement and Amendment (the "Lease Termination Agreement") with Bayside Area Development, LLC, a Delaware limited liability company (the "Landlord"), pursuant to which the Company and Landlord agreed to terminate that certain Lease, dated February 29, 2019, as amended (the "Original Lease"), related to the Company's office and laboratory space located at 285 E. Grand Avenue, South San Francisco, CA 94080. Prior to the Lease Termination Agreement, the term of the Original Lease was set to expire on December 31, 2029. Pursuant to the Lease Termination Agreement, the Original Lease will be terminated effective as of 11:59 p.m. on March 31, 2026 (the "Early Termination Date"), provided, that, Landlord has the right, at Landlord's option, upon at least thirty (30) days' prior written notice to the Company, to accelerate and designate an earlier Early Termination Date. As consideration for the Lease Termination Agreement, the Company agreed to pay Landlord approximately $3.65 million as prepaid rent in fulfillment of its rent obligations, consisting of $2.75 million paid by the Company concurrently with the execution of the Lease Termination Agreement and a right to draw down a letter of credit issued in the face amount of $0.90 million.

Additionally, in connection with the termination of the Original Lease, the Company entered into a Sublease Termination Agreement (the "Sublease Termination Agreement") with Initial Therapeutics, Inc., a Delaware corporation (the "Subtenant"), pursuant to which the Company and the Subtenant agreed to terminate that certain Sublease, dated May 24, 2022, as amended by the First Amendment to Sublease, dated September 14, 2023, related to the Company's sublease of office and laboratory space located at 285 E. Grand Avenue, South San Francisco, CA 94080, to the Subtenant. As consideration for the Sublease Termination Agreement, Subtenant paid the Company $0.20 million concurrently with execution of the Sublease Termination Agreement, which the Company is obligated to pay to Landlord within 10 days of receipt pursuant to the Lease Termination Agreement, and granted the Company the right to draw down a letter of credit in the face amount of $0.73 million, which the Company is obligated to draw down and pay the proceeds to Landlord pursuant to the Lease Termination Agreement, provided that, if the Company is unable to draw any such proceeds, the Company's agreement with Landlord will be unaffected.

Further, pursuant to the Lease Termination Agreement, in the event that the Company receives any cash consideration from the monetization, including through the issuance of equity or other securities, of the Company's corporate assets, within the period of September 24, 2025 through twenty-four (24) months following the Early Termination Date, Landlord is entitled to receive an amount equal to 25% of the value of such cash consideration up to a total aggregate amount of $26.9 million, which aggregate cap shall be reduced by an amount equal to the sum of prepaid rent received by Landlord. Such amount is to be paid by the Company to Landlord in cash within 30 days after the consummation of any such transaction.

As previously disclosed, in May 2025, the Company implemented a plan to reduce operating costs and preserve capital following the disclosure of full 36-weekdata from the Company's ASPIRE study, which included a reduction in force affecting all of the Company's employees. Further, in June 2025, the Company announced that the Board of Directors of the Company (the "Board") determined that it is in the best interests of the Company and its stockholders that the Company be dissolved, approved the voluntary dissolution of the Company (the "Dissolution") under the General Corporation Law of the State of Delaware (the "DGCL") pursuant to a Plan of Complete Liquidation and Dissolution (the "Plan of Dissolution"), and approved seeking stockholder approval to proceed with such dissolution. In light of such actions, the Company determined to terminate its lease.

The foregoing summary of the Lease Termination Agreement does not purport to be complete and is qualified in its entirety by the full text of the Lease Termination Agreement, a copy of which is filed herewith as Exhibit 10.1.

As previously reported, on June 27, 2025, the Board approved the Dissolution under the DGCL pursuant to the Plan of Dissolution. The Company's stockholders approved the Dissolution and Plan of Dissolution on September 18, 2025.

On September 26, 2025, as contemplated by the Plan of Dissolution, the Company filed a certificate of dissolution (the "Certificate of Dissolution") with the Secretary of the State of Delaware, which became effective as of 5:00 p.m. Eastern Time on September 26, 2025. For additional information regarding the Plan of Dissolution and the Dissolution, refer to the Company's Definitive Proxy Statement on Schedule 14A filed with the Securities and Exchange Commission on August 11, 2025.

Pursuant to and in accordance with the Plan of Dissolution, as of September 26, 2025, the Company has closed its transfer books, and shares of the Company's common stock, par value $0.0001 per share (the "Common Stock"), will no longer be assignable or transferable on the Company's books, other than transfers by will, intestate succession, operation of law or upon dissolution of such record holder or its successors. In addition, from and after the effectiveness of the Certificate of Dissolution, the Company's stockholders shall have only such rights and obligations as are provided for under the DGCL for stockholders of a dissolved corporation.

A copy of the Certificate of Dissolution is filed herewith as Exhibit 4.1 and is incorporated herein by reference.