Insight Guru Inc.
10/10/2026 | Press release | Distributed by Public on 10/10/2026 00:11
Market Movers | Winners: QSI, KLRA, FSLY | Losers: CDNL, ALHC, TMUS
On Friday, October 9, the S&P 500 gained 0.6%, the Nasdaq-100 rose 0.5% and the Dow Jones Industrial Average advanced 0.8%. Over the past week the S&P 500 is up 1.2%, and over the past month it is up 2.9%.
Within the Trefis coverage universe, 2,057 stocks rose and 2,035 fell. At the extremes, Quantum-Si (QSI) gained 25.4% and Cardinal Infrastructure (CDNL) fell 15.7%.
Friday's Market Winners
The 10 US-listed stocks in the Trefis coverage universe worth at least $300 million with the highest returns on Friday:
| # | Ticker | Company Name |
1-D Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | QSI | Quantum-Si | 25.4% | 39.1% |
| 2 | KLRA | Kailera Therapeutics | 16.1% | n/a |
| 3 | FSLY | Fastly | 15.9% | 187.8% |
| 4 | NVAX | Novavax | 15.8% | 89.7% |
| 5 | CCI | Crown Castle | 15.6% | -6.9% |
| 6 | DNA | Ginkgo Bioworks | 14.6% | 56.4% |
| 7 | MRNA | Moderna | 14.2% | n/a |
| 8 | ABSI | Absci | 13.6% | 191.1% |
| 9 | HUM | Humana | 11.6% | 69.9% |
| 10 | PRME | Prime Medicine | 11.5% | 15.0% |
Friday's Market Losers
And the 10 US-listed stocks in the Trefis coverage universe worth at least $300 million with the lowest returns on Friday:
| # | Ticker | Company Name |
1-D Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | CDNL | Cardinal Infrastructure | -15.7% | -12.7% |
| 2 | ALHC | Alignment Healthcare | -13.4% | -61.8% |
| 3 | TMUS | T-Mobile US | -13.3% | -25.6% |
| 4 | PKE | Park Aerospace | -11.1% | 25.8% |
| 5 | CCOI | Cogent Communications | -10.7% | -60.2% |
| 6 | ASTS | AST SpaceMobile | -10.5% | -29.8% |
| 7 | ATNI | ATN International | -10.3% | 15.3% |
| 8 | T | AT&T | -9.8% | -6.5% |
| 9 | SHEN | Shenandoah Telecommunications | -9.7% | -10.0% |
| 10 | IDR | Idaho Strategic Resources | -9.6% | -41.0% |
Some Of Friday's Biggest Moves Were Weeks In The Making
The 25.4% gain in Quantum-Si (QSI) on Friday was not a one-off: the stock is up 107.0% over the past month, and up 65.1% over the sessions before Friday.
Cardinal Infrastructure (CDNL) appears on both the one-day and one-month losers lists. It fell 15.7% on Friday and is down 38.1% over the past month; excluding Friday, it had already lost 26.5% over the other sessions.
Ginkgo Bioworks (DNA) added to a longer run: after Friday's 14.6% gain, the stock is up 91.7% over the past month, and it was already up 67.3% before Friday.
Movers Over The Last Week
Widening the window to five trading days, these are the strongest and weakest names in the Trefis coverage universe:
Winners
| # | Ticker | Company Name |
1-W Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | PCRX | Pacira BioSciences | 44.0% | 40.3% |
| 2 | OPCH | Option Care Health | 37.2% | -2.5% |
| 3 | PTC | PTC | 35.0% | 11.6% |
| 4 | PRME | Prime Medicine | 33.9% | 15.0% |
| 5 | PCVX | Vaxcyte | 26.4% | 54.7% |
| 6 | SCTX | Scribe Therapeutics | 26.1% | n/a |
| 7 | QDEL | QuidelOrtho | 24.6% | -53.0% |
| 8 | RXO | RXO | 24.4% | 130.1% |
| 9 | PENG | Penguin Solutions | 24.3% | 290.0% |
| 10 | NVAX | Novavax | 21.9% | 89.7% |
Losers
| # | Ticker | Company Name |
1-W Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | AVBP | ArriVent BioPharma | -40.8% | -16.8% |
| 2 | CDNL | Cardinal Infrastructure | -31.3% | -12.7% |
| 3 | ORBS | Eightco | -27.6% | -51.4% |
| 4 | ALMR | Alamar Biosciences | -26.5% | n/a |
| 5 | ANGO | AngioDynamics | -23.8% | -10.3% |
| 6 | GLAS | Glass House Brands | -22.4% | n/a |
| 7 | EOSE | Eos Energy Enterprises | -21.5% | -78.0% |
| 8 | AEHR | Aehr Test Systems | -21.1% | 319.2% |
| 9 | YSS | York Space Systems | -20.8% | n/a |
| 10 | AXTI | AXT | -20.3% | 318.7% |
Movers Over The Last Month
And over the last 21 trading days, the strongest and weakest names in the Trefis coverage universe:
Winners
| # | Ticker | Company Name |
1-M Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | QSI | Quantum-Si | 107.0% | 39.1% |
| 2 | DNA | Ginkgo Bioworks | 91.7% | 56.4% |
| 3 | PACB | Pacific Biosciences of California | 83.5% | 24.6% |
| 4 | GRAL | GRAIL | 81.3% | n/a |
| 5 | IOVA | Iovance Biotherapeutics | 79.6% | 435.5% |
| 6 | SECZ | Securitize | 71.9% | n/a |
| 7 | MRNA | Moderna | 64.7% | n/a |
| 8 | P | Everpure | 64.2% | n/a |
| 9 | FOSL | Fossil | 59.2% | 90.2% |
| 10 | PENG | Penguin Solutions | 56.9% | 290.0% |
Losers
| # | Ticker | Company Name |
1-M Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | LQDA | Liquidia | -59.6% | -20.6% |
| 2 | KDK | Kodiak AI | -56.1% | -84.7% |
| 3 | QURE | uniQure | -49.2% | -5.6% |
| 4 | EMAT | Evolution Metals & Technologies | -46.8% | n/a |
| 5 | GLAS | Glass House Brands | -46.6% | n/a |
| 6 | NKTR | Nektar Therapeutics | -41.7% | -2.6% |
| 7 | AVBP | ArriVent BioPharma | -41.7% | -16.8% |
| 8 | ALHC | Alignment Healthcare | -40.9% | -61.8% |
| 9 | ABR | Arbor Realty Trust | -40.3% | -59.2% |
| 10 | CDNL | Cardinal Infrastructure | -38.1% | -12.7% |
Volatility Is The Cost Of Owning Stocks. Concentration Makes It A Bill
Every name on these lists made a move big enough to notice. A diversified holder reads that as noise; a concentrated holder feels it as real money. The difference is not the stock, it is the portfolio around it.
Building that portfolio is what the Trefis High Quality (HQ) Portfolio does: roughly 30 businesses with the cash generation and balance-sheet strength to absorb bad days, selected and rebalanced by rules. It has a track record of outpacing a benchmark that combines the S&P 500, the S&P MidCap 400, and the Russell 2000. Let the movers list remind you why diversification exists.
Insight Guru Inc. published this content on October 10, 2026, and is solely responsible for the information contained herein. Distributed via Public Technologies (PUBT), unedited and unaltered, on October 10, 2026 at 06:11 UTC. If you believe the information included in the content is inaccurate or outdated and requires editing or removal, please contact us at [email protected]