Statement of Changes in Beneficial Ownership (Form 4)

FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b). Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940

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(Print or Type Responses)

1. Name and Address of Reporting Person * RENTON HOLLINGS 2. Issuer Name and Ticker or Trading Symbol ANAPTYSBIO, INC [ANAB] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) __X__ Director _____ 10% Owner _____ Officer (give title below) _____ Other (specify below) (Last) (First) (Middle) C/O ANAPTYSBIO, INC., 10770 WATERIDGE CIRCLE, SUITE 210 3. Date of Earliest Transaction (Month/Day/Year) 04/20/2026 (Street) SAN DIEGO, CA 92121 4. If Amendment, Date Original Filed (Month/Day/Year) 6. Individual or Joint/Group Filing (Check Applicable Line) _X_ Form filed by One Reporting Person ___ Form filed by More than One Reporting Person (City) (State) (Zip) Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned

1.Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price

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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)

1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Underlying Securities (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
Stock Option (right to buy)	$24.6	04/20/2026		D(1)			15,000	(2)	02/23/2027	Common Stock	15,000	$ 0	15,000	D
Stock Option (right to buy)	$18.03	04/20/2026		A(1)		15,000		(2)	02/23/2027	Common Stock	15,000	$ 0	15,000	D
Stock Option (right to buy)	$104.81	04/20/2026		D(1)			6,000	(2)	02/01/2028	Common Stock	6,000	$ 0	6,000	D
Stock Option (right to buy)	$76.79	04/20/2026		A(1)		6,000		(2)	02/01/2028	Common Stock	6,000	$ 0	6,000	D
Stock Option (right to buy)	$68.88	04/20/2026		D(1)			6,000	(2)	02/07/2029	Common Stock	6,000	$ 0	6,000	D
Stock Option (right to buy)	$50.47	04/20/2026		A(1)		6,000		(2)	02/07/2029	Common Stock	6,000	$ 0	6,000	D
Stock Option (right to buy)	$16.56	04/20/2026		D(1)			11,000	(2)	02/11/2030	Common Stock	11,000	$ 0	11,000	D
Stock Option (right to buy)	$12.14	04/20/2026		A(1)		11,000		(2)	02/11/2030	Common Stock	11,000	$ 0	11,000	D
Stock Option (right to buy)	$29.7	04/20/2026		D(1)			11,000	(2)	02/09/2031	Common Stock	11,000	$ 0	11,000	D
Stock Option (right to buy)	$21.76	04/20/2026		A(1)		11,000		(2)	02/09/2031	Common Stock	11,000	$ 0	11,000	D
Stock Option (right to buy)	$30.44	04/20/2026		D(1)			9,200	(2)	02/09/2032	Common Stock	9,200	$ 0	9,200	D
Stock Option (right to buy)	$22.13	04/20/2026		A(1)		9,200		(2)	02/09/2032	Common Stock	9,200	$ 0	9,200	D
Stock Option (right to buy)	$23.23	04/20/2026		D(1)			10,600	(2)	01/05/2033	Common Stock	10,600	$ 0	10,600	D
Stock Option (right to buy)	$17.02	04/20/2026		A(1)		10,600		(2)	01/05/2033	Common Stock	10,600	$ 0	10,600	D
Stock Option (right to buy)	$21.19	04/20/2026		D(1)			16,510	(2)	01/02/2034	Common Stock	16,510	$ 0	16,510	D
Stock Option (right to buy)	$15.53	04/20/2026		A(1)		16,510		(2)	01/02/2034	Common Stock	16,510	$ 0	16,510	D
Stock Option (right to buy)	$14.83	04/20/2026		D(1)			16,510	(2)	01/06/2035	Common Stock	16,510	$ 0	16,510	D
Stock Option (right to buy)	$10.87	04/20/2026		A(1)		16,510		(2)	01/06/2035	Common Stock	16,510	$ 0	16,510	D
Stock Option (right to buy)	$43.91	04/20/2026		D(1)			5,500	(3)	01/06/2036	Common Stock	5,500	$ 0	5,500	D
Stock Option (right to buy)	$32.17	04/20/2026		A(1)		5,500		(3)	01/06/2036	Common Stock	5,500	$ 0	5,500	D

Reporting Owners

Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
RENTON HOLLINGS C/O ANAPTYSBIO, INC. 10770 WATERIDGE CIRCLE, SUITE 210 SAN DIEGO, CA 92121	X

Signatures

/s/ Dan Faga, Attorney-in-Fact		04/22/2026
**Signature of Reporting Person		Date

Explanation of Responses:

*	If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1)	Effective as of a pro rata distribution by AnaptysBio to holders of its shares of common stock pursuant to the Separation and Distribution Agreement dated as of April 20, 2026, by and between AnaptysBio and First Tracks (the "Separation Agreement"), each outstanding option to acquire AnaptysBio shares of common stock was adjusted so that such option became an option to acquire First Tracks shares of common stock and an option to acquire AnaptysBio shares of common stock. As a result, the Reporting Person acquired options to acquire AnaptyBio shares of common stock in an amount determined in accordance with the Separation Agreement.
(2)	The stock option is fully vested and exercisable.
(3)	The stock option vests as to 1/12 of the total shares monthly commencing on February 6, 2026 until fully vested, subject to the Reporting Person's provision of service to the Issuer on each vesting date.

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