Insight Guru Inc.
10/29/2026 | Press release | Distributed by Public on 10/29/2026 03:32
The 52-Week-High List: 11 Large Cap Names On Wednesday
As of Wednesday, October 28, there are 11 Large Cap US and Canada-listed stocks in the Trefis coverage universe trading at their 52-week highs. Large Cap here means a market value above $40 billion.
Thermo Fisher Scientific (TMO), with a market value of about $261.2 billion, is the largest company on the list; its stock is up 3.6% over the past month and up 25.3% over the past year. Health Care contributed the most names, 5 of the 11. For context, the S&P 500 is up 1.0% over the past month, including dividends.
The 10 Largest, By Market Cap
The table below shows the 10 largest of the 11 names, sorted by market capitalization, with returns over four windows:
| Tickers |
Market Cap |
1D Return |
1W Return |
1M Return |
1Y Return |
|---|---|---|---|---|---|
| TMO | $261.2 Bil | 1.6% | 1.5% | 3.6% | 25.3% |
| AMGN | $244.0 Bil | 0.9% | 3.1% | 6.7% | 59.5% |
| TD | $208.2 Bil | 0.5% | 1.4% | 7.0% | 59.6% |
| GILD | $197.9 Bil | 0.1% | 3.7% | 5.2% | 35.4% |
| BNS | $115.6 Bil | 0.7% | 0.6% | 3.2% | 50.9% |
| EMR | $93.7 Bil | 0.9% | 2.8% | 6.7% | 26.7% |
| URI | $73.0 Bil | 1.1% | 9.9% | 15.8% | 31.5% |
| TRGP | $65.6 Bil | 1.1% | 3.5% | 11.9% | 102.9% |
| NDAQ | $59.0 Bil | 1.1% | 9.8% | 14.9% | 20.5% |
| A | $51.2 Bil | 2.2% | 2.1% | 3.8% | 24.7% |
The Businesses Behind The Largest New Highs
Thermo Fisher Scientific (TMO) trades at 37.5 times trailing earnings, grew revenue 7.2% over the last twelve months and earned an operating margin of 18.3%.
Amgen (AMGN) trades at 27.9 times trailing earnings, grew revenue 9.1% over the last twelve months and earned an operating margin of 30.0%.
Across the list, one-month moves range from +3.2% for Bank of Nova Scotia (BNS) to +15.8% for United Rentals (URI).
Over the past year, the median name here is up 35.4%.
9 of the 11 names are also S&P 500 members.
A new high tells you what the market already believes. The harder question is which of these runs management itself is underwriting. Our Guidance Momentum screen tracks exactly that: stocks where the company raised its own forward numbers.
One more pattern worth noticing: 5 of the 11 names are Health Care stocks. When a whole group is making new highs together, a health care ETF like XLV, which holds 5 of the 5 largest of them, is one way to own part of the group's strength without betting on which single name leads it from here.
New Highs Fade. Discipline Compounds
Some of the names on this list will keep setting highs for years, and some are at the top of their run right now. Sorting one from the other, name by name, every day, is the work most investors never keep up with.
That sorting is what the Trefis High Quality (HQ) Portfolio does systematically: about 30 quality businesses screened for the fundamentals that sustain a run, held with rules instead of excitement. It has a track record of outpacing a benchmark that combines the S&P 500, the S&P MidCap 400, and the Russell 2000. Use the high list for ideas; use the portfolio for the compounding.
Insight Guru Inc. published this content on October 29, 2026, and is solely responsible for the information contained herein. Distributed via Public Technologies (PUBT), unedited and unaltered, on October 29, 2026 at 09:32 UTC. If you believe the information included in the content is inaccurate or outdated and requires editing or removal, please contact us at [email protected]