Sioux Falls Woman Sentenced to 20 Years in Federal Prison for Distributing the Fentanyl that Killed Another Woman

SIOUX FALLS - United States Attorney Ron Parsons announced today that U.S. District Judge Karen E. Schreier has sentenced a Sioux Falls, South Dakota, woman convicted of Distribution of a Controlled Substance Resulting in Death. The sentencing took place on March 2, 2026.

Anastasia Muggins, 33, was sentenced to 20 years in federal prison, followed by five years of supervised release, and ordered to pay a $100 special assessment to the Federal Crime Victims Fund.

Muggins was indicted for Distribution of a Controlled Substance Resulting in Death by a federal grand jury in May 2025. She pleaded guilty on December 11, 2025.

On December 15, 2024, Sheila Eastman, who was born in Flandreau and was an enrolled member of the Flandreau Santee Sioux Tribe, was found deceased in her Sioux Falls residence. The coroner concluded Eastman died from fentanyl toxicity. Sioux Fall Police Detectives investigated the case and determined Muggins had distributed approximately 0.1 grams of fentanyl powder to Ms. Eastman. She ingested it and died.

"On December 15, 2025, the one-year anniversary of the death of Sheila Eastman from fentanyl poisoning, this Administration issued an Executive Order officially designating fentanyl as a weapon of mass destruction," said U.S. Attorney Parsons. "As this case tragically shows, illicit fentanyl is much closer to a chemical weapon than a simple narcotic. Just two milligrams, an almost undetectable trace amount equivalent to 10 to 15 grains of table salt, is a lethal dose. Hundreds of thousands of Americans like Sheila have been killed by the fentanyl smuggled into this country from China and the Mexican drug cartels. We are committed to doing everything we can to put an end to the death and misery these chemical weapons continue to cause."

This case was investigated by the Sioux Falls Police Department and the Drug Enforcement Administration. Assistant U.S. Attorney Mark Hodges prosecuted the case.

Muggins was immediately remanded to the custody of the U.S. Marshals Service.