Children's National Medical Center Inc.

09/18/2026 | Press release | Distributed by Public on 09/19/2026 22:56

What is Multisystem Inflammatory Syndrome in Children (MIS-C)? - Children's National

Please note: As we continue to learn more about COVID-19, the information in this article may change. You can find our most up-to-date information about coronavirus here.

If you've been keeping up with the news lately, you've probably heard about an illness called Multisystem Inflammatory Syndrome in Children (MIS-C) that's affecting children who have had COVID-19. Doctors and researchers are still trying to learn about this disease, but here's what we know so far.

Symptoms of MIS-C

MIS-C is a condition in which different body parts become inflamed, such as the heart, lungs, kidneys, brain, gastrointestinal tract, skin or eyes. Children with MIS-C can have a variety of symptoms, including:

  • Fever
  • Abdominal Pain
  • Vomiting
  • Diarrhea
  • Neck Pain
  • Rash
  • Bloodshot Eyes
  • Feeling Extra Tired

If your child experiences the following more severe versions of MIS-C symptoms, you should seek emergency care immediately:

  • Trouble breathing
  • Pain or pressure in the chest that does not go away
  • New confusion
  • Inability to wake or stay awake
  • Pale, gray, or blue-colored skin, lips, or nail beds, depending on skin
  • Severe abdominal pain

What causes MIS-C?

We do not yet know what causes MIS-C, however many children with MIS-C have tested positive for the novel coronavirus (COVID-19). We also don't know if children with certain health conditions are more likely to get MIS-C than others. Fortunately, unlike COVID-19, MIS-C does not appear to be contagious. MIS-C is also a relatively rare condition - less than 10 percent of patients that test positive for COVID-19 contract MIS-C.

The link between MIS-C and COVID-19 is evolving every day, and pediatricians and researchers at Children's National Hospital and the Centers for Disease Control (CDC) are working tirelessly to understand its current and long-term effects on children.

While MIS-C is a serious condition, with proper medical care most children are able to recover. If you have concerns your child is suffering from MIS-C, please call your primary care provider.

Children's National Medical Center Inc. published this content on September 18, 2026, and is solely responsible for the information contained herein. Distributed via Public Technologies (PUBT), unedited and unaltered, on September 20, 2026 at 04:56 UTC. If you believe the information included in the content is inaccurate or outdated and requires editing or removal, please contact us at [email protected]