Material Agreement (Form 8-K)

Item 1.01 Entry into a Material Definitive Agreement.

On June 30, 2026, INmune Bio Inc. (the Company") entered into a warrant inducement offer letter agreement (the "Inducement Letter") and into an amendment to common stock purchase warrant (the "Second Amendment") with certain holders (the "Holders") of common stock purchase warrants previously issued by the Company in its April 2024 offerings on April 24, 2024 and April 29, 2024, as such warrants were amended on December 22, 2025 (the "April 2024 Warrants").

Pursuant to the Inducement Letter the Company offered the Holders the opportunity to exercise 50% of the April 2024 Warrants held by them for a reduced exercise price per share equal to $1.40 (reduced from $1.95) (the "Reduced Exercise Price") and to amend the April 2024 Warrants such that the maturity date of the April 2024 Warrants, as it relates to the remaining 50% of the April 2024 Warrants that were not exercised pursuant to the Inducement Letter, shall be extended from June 30, 2026, to December 31, 2027.

Pursuant to the Inducement Letter, Holders agreed to exercise, for cash, 647,112 April 2024 Warrants, representing 50% of the April 2024 Warrants held by such Holders, and have agreed to purchase an aggregate of 647,112 shares of common stock at the Reduced Exercise Price in exchange for the Company's agreement to extend the maturity date of the April 2024 Warrants, as it relates to the remaining 50% of the April 2024 Warrants that were not exercised pursuant to the Inducement Letter, from June 30, 2026, to December 31, 2027. The Company expects to receive an aggregate of $905,957 as consideration for the exercise of the said 50% of the April 2024 Warrants.

Pursuant to the Second Amendment, the maturity date of the April 2024 Warrants, as it relates to the remaining 50% of the April 2024 Warrants that were not exercised pursuant to the Inducement Letter, was extended from June 30, 2026, to December 31, 2027.

The issuance, or resale, of shares of common stock underlying the April 2024 Warrant have been registered pursuant to an effective registration statement (File No. 333-279036). The Registration Statement is currently effective and, upon exercise of 50% the April 2024 Warrant pursuant to Inducement Letter will be effective for the issuance or resale of the shares of common stock underlying the April 2024 Warrants, as applicable.

The foregoing summary of the Inducement Letter and the Second Amendment does not purport to be complete and is qualified in its entirety by reference to the form of the Inducement Letter and the Second Amendment, a copy of which is filed as Exhibits 4.1 and 10.1 hereto and incorporated herein by reference.