Statement of Changes in Beneficial Ownership (Form 4)

FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b). Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940

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(Print or Type Responses)

1. Name and Address of Reporting Person * Meister Keith A. 2. Issuer Name and Ticker or Trading Symbol ILLUMINA, INC. [ILMN] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) __X__ Director _____ 10% Owner _____ Officer (give title below) _____ Other (specify below) (Last) (First) (Middle) C/O CORVEX MANAGEMENT LP, 667 MADISON AVENUE 3. Date of Earliest Transaction (Month/Day/Year) 08/19/2026 (Street) NEW YORK, NY 10065 4. If Amendment, Date Original Filed (Month/Day/Year) 6. Individual or Joint/Group Filing (Check Applicable Line) _X_ Form filed by One Reporting Person ___ Form filed by More than One Reporting Person (City) (State) (Zip) Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned

1.Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock 08/19/2026 S 19,884 D $202.37(3) 2,069,541 I See Footnotes(1)(2) Common Stock 08/19/2026 S 57,544 D $203.16(4) 2,011,997 I See Footnotes(1)(2) Common Stock 08/19/2026 S 4,759 D $204.16(5) 2,007,238 I See Footnotes(1)(2) Common Stock 08/19/2026 S 12,813 D $205(6) 1,994,425 I See Footnotes(1)(2) Common Stock 08/20/2026 S 1,132 D $207.65(7) 1,993,293 I See Footnotes(1)(2) Common Stock 08/20/2026 S 3,563 D $208.55(8) 1,989,730 I See Footnotes(1)(2) Common Stock 08/20/2026 S 9,078 D $209.68(9) 1,980,652 I See Footnotes(1)(2) Common Stock 08/20/2026 S 23,638 D $210.66(10) 1,957,014 I See Footnotes(1)(2) Common Stock 08/20/2026 S 34,009 D $211.90(11) 1,923,005 I See Footnotes(1)(2) Common Stock 08/20/2026 S 29,805 D $212.83(12) 1,893,200 I See Footnotes(1)(2) Common Stock 08/20/2026 S 71,939 D $213.36(13) 1,821,261 I See Footnotes(1)(2) Common Stock 08/20/2026 S 42,218 D $214.57(14) 1,779,043 I See Footnotes(1)(2) Common Stock 08/20/2026 S 18,405 D $215.62(15) 1,760,638 I See Footnotes(1)(2) Common Stock 08/20/2026 S 15,263 D $216.88(16) 1,745,375 I See Footnotes(1)(2) Common Stock 08/20/2026 S 21,147 D $217.72(17) 1,724,228 I See Footnotes(1)(2) Common Stock 08/20/2026 S 5,693 D $218.46(18) 1,718,535 I See Footnotes(1)(2) Common Stock 08/20/2026 S 9,348 D $219.82(19) 1,709,187 I See Footnotes(1)(2) Common Stock 08/21/2026 S 4,528 D $210.45(20) 1,704,659 I See Footnotes(1)(2) Common Stock 08/21/2026 S 7,151 D $211.54(21) 1,697,508 I See Footnotes(1)(2) Common Stock 08/21/2026 S 13,050 D $212.65(22) 1,684,458 I See Footnotes(1)(2) Common Stock 08/21/2026 S 6,821 D $213.81(23) 1,677,637 I See Footnotes(1)(2) Common Stock 08/21/2026 S 13,668 D $214.64(24) 1,663,969 I See Footnotes(1)(2) Common Stock 08/21/2026 S 9,365 D $215.61(25) 1,654,604 I See Footnotes(1)(2) Common Stock 08/21/2026 S 12,602 D $216.44(26) 1,642,002 I See Footnotes(1)(2) Common Stock 08/21/2026 S 8,187 D $217.84(27) 1,633,815 I See Footnotes(1)(2) Common Stock 08/21/2026 S 86,825 D $218.6(28) 1,546,990 I See Footnotes(1)(2) Common Stock 08/21/2026 S 133,256 D $219.47(29) 1,413,734 I See Footnotes(1)(2) Common Stock 08/21/2026 S 3,883 D $220.13(30) 1,409,851 I See Footnotes(1)(2) Common Stock 6,780 D

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)

1. Title of Derivative Security (Instr. 3)

2. Conversion or Exercise Price of Derivative Security

3. Transaction Date (Month/Day/Year)

3A. Deemed Execution Date, if any (Month/Day/Year)

4. Transaction Code (Instr. 8)

5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5)

6. Date Exercisable and Expiration Date (Month/Day/Year)

7. Title and Amount of Underlying Securities (Instr. 3 and 4)

8. Price of Derivative Security (Instr. 5)

9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)

10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)

11. Nature of Indirect Beneficial Ownership (Instr. 4)

Code

V

(A)

(D)

Date Exercisable

Expiration Date

Title

Amount or Number of Shares

Reporting Owners

Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
Meister Keith A. C/O CORVEX MANAGEMENT LP 667 MADISON AVENUE NEW YORK, NY 10065	X

Signatures

/s/ Keith Meister		08/21/2026
**Signature of Reporting Person		Date

Explanation of Responses:

*	If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1)	These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.
(2)	For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.
(3)	The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $201.59 to $202.58. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes (3)-(30) to this Form 4.
(4)	The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $202.59 to $203.58.
(5)	The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $203.65 to $204.61.
(6)	The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $204.72 to $205.11.
(7)	The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $207.01 to $207.91.
(8)	The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $208.02 to $209.01.
(9)	The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $209.11 to $210.10.
(10)	The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $210.11 to $211.09.
(11)	The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $211.14 to $212.13.
(12)	The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $212.14 to $213.12.
(13)	The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $213.14 to $214.13.
(14)	The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $214.14 to $215.11.
(15)	The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $215.14 to $216.13.
(16)	The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $216.14 to $217.13.
(17)	The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $217.14 to $218.13.
(18)	The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $218.14 to $219.13.
(19)	The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $219.15 to $220.00.
(20)	The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $210.01 to $210.99.
(21)	The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $211.06 to $212.04.
(22)	The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $212.06 to $213.05.
(23)	The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $213.07 to $214.06.
(24)	The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $214.07 to $215.06.
(25)	The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $215.07 to $216.06.
(26)	The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $216.07 to $217.06.
(27)	The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $217.07 to $218.05.
(28)	The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $218.07 to $219.06.
(29)	The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $219.07 to $220.06.
(30)	The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $220.07 to $220.43.

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