Change in Certifying Accountants (Form 8-K)

The Board of Directors of CNBX Pharmaceuticals Inc. (the "Company") has dismissed Elkana Amitai CPA ("Former Accounting Firm") as its independent registered public accounting firm, effective as of September 28th, 2026. As described in Item 4.01(a) below, the change in independent registered public accounting firm is not the result of any disagreement with the Former Accounting Firm. The Board made the decision to dismiss the Former Accounting Firm acting under authority delegated to it and the Board of Directors approved the same on September 28th, 2026. On the same date, the Board of Directors of the Company engaged Vilki & Co-#1 Luxor Palace, Gandhi Smruti Bhavan, Gujarat, India 394651 (the "New Accounting Firm") as its new independent accounting firm as of and for the year ended August 31^st, 2026.

The Former Accounting Firm's audit reports on the Company's consolidated financial statements as of and for the fiscal years ended August 31^st, 2024 and 2025 did not contain an adverse opinion or a disclaimer of opinion and were not qualified or modified as to uncertainty, audit scope or accounting principles, except that Former Accounting Firm's reports, on the Company's consolidated financial statements as of and for the fiscal years ended August 31^st, 2024 and 2025included an explanatory paragraph indicating that there was substantial doubt about the Company's ability to continue as a going concern.

During the years ended August 31, 2025 and 2026, and through the Dismissal Date, there were (i) no disagreements between the Company and Former Accounting Firm Elkana Amitai CPA on any matter of accounting principles or practices, financial statement disclosure, or auditing scope or procedures, which disagreement, if not resolved to the satisfaction of Elkana Amitai CPA, would have caused them to make reference thereto in their reports on the consolidated financial statements for such years, and (ii) no "reportable events" as that term is defined in Item 304(a)(1)(v) of Regulation S-K

The Company has not consulted with the New Accounting Firm during our two most recent fiscal years or during any subsequent interim period prior to its appointment as New Accounting Firm regarding either (i) the application of accounting principles to a specified transaction, either completed or proposed; or the type of audit opinion that might be rendered on our financial statements, and neither a written report was provided to us nor oral advice was provided that the New Accounting Firm concluded was an important factor considered by the Company in reaching a decision as to the accounting, auditing or financial reporting issue; or (ii) any matter that was either the subject of disagreement (as defined in Item 304(a)(1)(iv) of Regulation S-K and the related instructions) or a reportable event (within the meaning of Item 304(a)(1)(v) of Regulation S-K).

The Company has requested that the Former Accounting Firm furnish it with a letter addressed to the Securities and Exchange Commission stating whether or not it agrees with the above statement. A copy of the letter from the Former Accounting Firm is attached hereto as Exhibit 16.1 to this Form 8-K