Failure to Satisfy Listing Rule (Form 8-K)

Item 3.01 Notice of Delisting or Failure to Satisfy a Continued Listing Rule or Standard; Transfer of Listing.

On September 15, 2026, Moleculin Biotech, Inc. (the "Company") received a letter (the "Staff Determination Letter") from the Listing Qualifications Department (the "Staff") of The Nasdaq Stock Market LLC ("Nasdaq") notifying the Company that the Staff has determined that the closing bid price of the Company's common stock, par value $0.001 per share (the "Common Stock"), has been below $1.00 per share for the previous 30 consecutive business days (from July 31, 2026 through September 11, 2026) and, as a result, the Company is not in compliance with the minimum bid price requirement for continued listing on The Nasdaq Capital Market set forth in Nasdaq Listing Rule 5550(a)(2) (the "Minimum Bid Price Requirement").

Ordinarily, a company that fails to meet the Minimum Bid Price Requirement would be afforded a 180-calendar day compliance period pursuant to Nasdaq Listing Rule 5810(c)(3)(A) to regain compliance. However, pursuant to Nasdaq Listing Rule 5810(c)(3)(A)(iv), the Staff has determined that the Company is not eligible for any compliance period specified in Nasdaq Listing Rule 5810(c)(3)(A), because the Company has effected a reverse stock split in the prior one-year period. As previously disclosed, the Company effected a 1-for-25 reverse stock split of the Common Stock on December 1, 2025.

The Company intends to make a timely request for a hearing before the Nasdaq Hearings Panel (the "Panel"), in accordance with the procedures set forth in the Nasdaq Listing Rule 5800 Series. A timely request for a hearing will stay any suspension or delisting action pending the Panel's decision, and the Company's Common Stock will continue to trade on The Nasdaq Capital Market during the pendency of the hearing process. There can be no assurance that the Company's request for continued listing will be granted or that the Company will be able to regain and maintain compliance with the Minimum Bid Price Requirement or all other applicable requirements for continued listing on The Nasdaq Capital Market.