FORM 3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940

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(Print or Type Responses)

1. Name and Address of Reporting Person * Ennis Riley Charles 2. Date of Event Requiring Statement (Month/Day/Year) 07/20/2026 3. Issuer Name and Ticker or Trading Symbol Freenome, Inc. [FRNM] (Last) (First) (Middle) C/O FREENOME, INC., 51 ASTOR PLACE, 10TH FLOOR 4. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director _____ 10% Owner __X__ Officer (give title below) _____ Other (specify below) Chief Product Officer 5. If Amendment, Date Original Filed (Month/Day/Year) (Street) NEW YORK, NY 10003 6. Individual or Joint/Group Filing (Check Applicable Line) _X_ Form filed by One Reporting Person ___ Form filed by More than One Reporting Person (City) (State) (Zip) Table I - Non-Derivative Securities Beneficially Owned

1.Title of Security (Instr. 4) 2. Amount of Securities Beneficially Owned (Instr. 4) 3. Ownership Form: Direct (D) or Indirect (I) (Instr. 5) 4. Nature of Indirect Beneficial Ownership (Instr. 5) Common Stock 2,490,453 D Common Stock 373,913 I By Trust(1)

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.			SEC 1473 (7-02)
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Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)

1. Title of Derivative Security (Instr. 4)	2. Date Exercisable and Expiration Date (Month/Day/Year)		3. Title and Amount of Securities Underlying Derivative Security (Instr. 4)		4. Conversion or Exercise Price of Derivative Security	5. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 5)	6. Nature of Indirect Beneficial Ownership (Instr. 5)
	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
Stock Option (right to buy)	(2)	06/21/2030	Common Stock	310,958	$4.85	D
Stock Option (right to buy)	(2)	06/21/2032	Common Stock	281,369	$15.91(6)	D
Stock Option (right to buy)	(3)	02/17/2033	Common Stock	75,082	$11.88(6)	D
Stock Option (right to buy)	(4)	02/15/2034	Common Stock	118,471	$18.24(6)	D
Stock Option (right to buy)	(5)	03/10/2035	Common Stock	221,457	$14(6)	D

Reporting Owners

Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
Ennis Riley Charles C/O FREENOME, INC. 51 ASTOR PLACE, 10TH FLOOR NEW YORK, NY 10003			Chief Product Officer

Signatures

/s/ Thomas Fitzpatrick, Attorney-in-Fact		07/27/2026
**Signature of Reporting Person		Date

Explanation of Responses:

*	If the form is filed by more than one reporting person, see Instruction 5(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1)	Represents shares held by the Riley Ennis Irrevocable Trust dated 1/14/21. The Reporting Person disclaims beneficial ownership of such shares for purposes of Section 16 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), except to the extent of his pecuniary interest therein, if any. This report shall not be deemed an admission that he is a beneficial owner of such shares for the purpose of Section 16 of the Exchange Act, or for any other purpose.
(2)	The shares subject to this option are fully vested.
(3)	25% of the shares subject to this option shall vest and become exercisable on February 2, 2024 with the remainder vesting in thirty-six (36) equal monthly installments thereafter, subject to the Reporting Person's continued service on each such vesting date.
(4)	The shares subject to this option shall vest and become exercisable in thirty-six (36) equal monthly installments commencing from February 16, 2024, subject to the Reporting Person's continued service on each such vesting date.
(5)	25% of the shares subject to this option shall vest and become exercisable on February 15, 2026 with the remainder vesting in thirty-six (36) equal monthly installments thereafter, subject to the Reporting Person's continued service on each such vesting date.
(6)	This option was previously amended, pursuant to which the exercise price of the option will be automatically reduced to $8.45 upon the occurrence of certain events.
Remarks: Exhibit 24 - Power of Attorney

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