Morgan Stanley Institutional Fund Inc.

05/05/2026 | Press release | Distributed by Public on 05/05/2026 13:41

Prospectus Certification by Investment Company (Form 497J)

1095 Avenue of the Americas
New York, NY 10036-6797

+1 212 698 3500 Main

+1 212 698 3599 Fax

www.dechert.com

VIA EDGAR

May 5, 2026

Securities and Exchange Commission

100 F Street, N.E.

Washington, D.C. 20549

Re: Morgan Stanley Institutional Fund, Inc.
File Nos. 33-23166; 811-05624
Post-Effective Amendment No. 265

Ladies and Gentlemen:

On behalf of Morgan Stanley Institutional Fund, Inc. ("Registrant") and pursuant to Rule 497(j) under the Securities Act of 1933, as amended (the "Securities Act"), I hereby certify that (i) the forms of prospectuses contained in Post-Effective Amendment No. 265 to Registrant's Registration Statement on Form N-1A, filed on April 30, 2026, constituting the most recent amendment to this Registration Statement (the "Amendment"), that would have been filed pursuant to Rule 497(c) under the Securities Act would not have differed from those contained in the Amendment, and (ii) the text of the Amendment was filed electronically with the Securities and Exchange Commission on April 30, 2026, accession number 0001133228-26-007524.

If you have any questions, please feel free to contact me at 212.698.3526 (tel) or 212.698.3599 (fax).

Very truly yours,
/s/ Allison Fumai
Allison Fumai
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